Publications by authors named "Anna Hasegawa"
Article Synopsis
- The study aimed to collect real-world data on VEXAS syndrome, focusing on disease activity, treatments, remission rates, and adverse events over a prospective period.
- Researchers enrolled suspected patients in Japan, utilizing a new disease activity measure (VEXASCAF) and recorded various health metrics, including UBA1 gene variant analysis.
- Out of 55 patients, 30 were found to have pathogenic UBA1 variants, with limited remission reported, frequent adverse events including deaths and infections, and a need for high-dose glucocorticoids to manage symptoms.
To clarify the differences and similarities in the cytokine profiles of macrophage activating syndrome (MAS) between systemic lupus erythematosus (SLE) and adult-onset Still's disease (AOSD). The study participants included 9 patients with MAS-SLE, 22 with non-MAS-SLE, 9 with MAS-AOSD, and 13 with non-MAS-AOSD. Serum cytokine levels were measured using a multiplex bead assay.
View Article and Find Full Text PDFBackground: As a first step in identifying the developmental pathways of pulmonary abnormalities in rheumatoid arthritis (RA), we sought to determine the existing and changing patterns of pulmonary abnormalities.
Methods: We conducted a retrospective cohort study of consecutive patients with RA who underwent high-resolution computed tomography before and during biologic therapy. The presence of 20 pulmonary abnormalities and the changes in those abnormalities were recorded.