Medicine (Baltimore)
September 2018
Rationale: Celiac disease (CD) is an autoimmune disorder induced by dietary gluten in genetically predisposed subjects. Activation of the hypothalamic-pituitary-axis (HPA) can occur in patients with CD; however, this condition has never been described in overweight/obese CD children.
Patient Concerns: A 12-year-old girl with CD was admitted with mild acanthosis nigricans of the armpits, groin and neck.