Does the site of research evidence generation impact on its translation to clinical practice? A protocol paper.

The research-to-practice gap is a well-known phenomenon. The adoption of evidence into clinical practice needs to consider the complexity of the health care system and a multitude of contextual issues. Research evidence is usually a form of extrinsic motivation for practice change, but works best when it aligns with the intrinsic values of the system and the people in it.

Early thrombosis after iliac stenting for venous outflow occlusion is related to disease severity and type of anticoagulation.

Background: Stenting of the iliac venous system is often performed for symptomatic obstruction, with high patency rates reported. However, patients with post-thrombotic disease and those with more extensive obstruction have experienced poorer outcomes, including a higher rate of early post-stent thrombosis. In the present study, we examined the outcomes of patients with complete venous outflow occlusion.

What works, why and how? A scoping review and logic model of rural clinical placements for allied health students.

Background: Allied health services are core to the improvement in health outcomes for remote and rural residents. Substantial infrastructure has been put into place to facilitate rural work-ready allied health practitioners, yet it is difficult to understand or measure how successful this is and how it is facilitated.

Methods: A scoping review and thematic synthesis of the literature using program logic was undertaken to identify and describe the contexts, mechanisms and outcomes of successful models of rural clinical placements for allied health students.

Decreased hepatocellular carcinoma tumor burden with the achievement of hepatitis C virus sustained virologic response: unlocking the potential of T-cell-mediated immunosurveillance.

We describe two cases of patients with hepatitis C virus (HCV) treated with direct-acting antiviral (DAA) therapy who had dramatic improvement in hepatocellular carcinoma (HCC) tumor burden with DAA therapy alone. Both patients were diagnosed with HCC on screening magnetic resonance imaging shortly after beginning DAA therapy. Both patients achieved sustained virologic response (SVR) with dramatic improvement in HCC tumor burden on follow-up imaging without HCC treatment.

Pacific acuity test: testability, validity, and interobserver reliability.

Purpose: The Pacific Acuity Test (PAT) is a new vanishing optotype test designed to measure recognition visual acuities in preverbal children using a face and opposing oval figure in a forced-choice preferential looking format. This study evaluates the testability, validity, and interobserver reliability of the PAT.

Methods: Fifty-two subjects, aged 6 to 36 months, were tested by a primary observer to determine both recognition and resolution visual acuities using the PAT.