Publications by authors named "Anna G Kostopoulou"
Article Synopsis
- Iron buildup, inflammation, and genetic factors contribute to heart problems in patients with β-thalassemia major, affecting the left atrium and ventricle.
- In a study with 90 β-thalassemia patients and 90 healthy controls, it was found that atrial dysfunction occurs earlier than notable left ventricular issues, with significant changes in echocardiographic measurements as patients age.
- Elevated levels of certain peptides (NT-proBNP and proANP) in patients indicate worse heart function, and a subset of patients experienced atrial fibrillation, highlighting early signs of cardiac damage.
Article Synopsis
- - An 83-year-old patient with a pacemaker infection experienced dislodgment of pacemaker leads after the generator and part of the leads were removed, leaving some leads abandoned.
- - After 25 days, the abandoned leads became dislodged, leading to a systemic infection.
- - The dislodged leads were surgically removed without any further complications.
Background: The early diagnosis and treatment of heart failure in beta-thalassaemic patients is related to survival. Iron alone or in combination with other factors causes diastolic dysfunction, which usually precedes systolic dysfunction. NT-proBNP is a sensitive biomarker of ventricular dysfunction.
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