Publications by authors named "Anna Furiano"
Recent findings suggest that soluble forms of amyloid-β (sAβ) peptide contribute to synaptic and cognitive dysfunctions in early stages of Alzheimer's disease (AD). On the other hand, neuroinflammation and cyclooxygenase-2 (COX-2) enzyme have gained increased interest as key factors involved early in AD, although the signaling pathways and pathophysiologic mechanisms underlying a link between sAβ-induced neurotoxicity and inflammation are still unclear. Here, we investigated the effects of selective COX-2 enzyme inhibition on neuropathological alterations induced by sAβ administration in rats.
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- Myocardial infarction (MI) is a major cause of death in developed countries, linked with various symptoms and decreased quality of life, and recent studies indicate a relationship between heart issues and brain inflammation.
- Researchers examined the effects of MI on specific brain cells (microglia and astrocytes) in sedentary and trained rats, discovering notable changes in these cells 48 hours post-MI.
- Prolonged exercise was found to reverse some of the brain changes caused by MI, particularly in areas like the prefrontal cortex, hippocampus, and thalamus, suggesting that physical activity can help mitigate brain inflammation related to heart problems.