Publications by authors named "Anna Dominguez Guasch"

Article Synopsis
  • Acute myeloid leukemia (AML) is usually not linked to secondary hemolytic-uremic syndrome (HUS), but this case report presents an exception.
  • A woman diagnosed with AML developed severe HUS, and her condition improved significantly after receiving eculizumab, a medication that helped stabilize her health.
  • After one year with normal renal function and genetic tests, she was able to stop eculizumab, underscoring the importance of early treatment for secondary HUS in improving patient outcomes.
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Purpose: Renal injury is common in cancer patients and its etiology is multifactorial. Different patterns of renal histological lesions have been described in relation to oncologic treatments, notably acute tubular necrosis and tubulointerstitial nephritis, but also thrombotic microangiopathy (TMA).

Methods: We report a case of TMA secondary to capecitabine in an 82-year-old woman diagnosed with localized colon adenocarcinoma.

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