Publications by authors named "Anna D Pljutinskaya"
Free Radic Biol Med
February 2006
Article Synopsis
- Reactive oxygen species produced by specialized photosensitizers called cycloimide derivatives of bacteriochlorin p (CIBCs) show promise for effectively treating tumors.
- These CIBCs have been engineered to absorb light in a range that penetrates tissues (780-830 nm) and demonstrate remarkable stability under light exposure, making them more effective phototoxic agents—300 times more so than the commonly used photosensitizer Photogem.
- The design of these CIBCs allows for selective targeting of cancer cell organelles such as lipid droplets and the Golgi apparatus, which are highly sensitive to light-induced damage, enhancing their potential for effective photodynamic therapy.
