Publications by authors named "Anna Carolina R Tempestini Horliana"
J Periodontal Res
April 2024
Article Synopsis
- - The study explores how high glucose levels affect human periodontal ligament (PL) cells, focusing on their shape, movement, and ability to stick to surfaces due to changes in specific microRNAs (miR-221 and miR-222).
- - Results indicate that high glucose reduces PL cell adhesion and migration, leading to unstable cell structures and impaired healing processes, particularly relevant for patients with unmanaged diabetes.
- - The findings suggest that the negative impacts of high glucose on PL cells may be linked to the downregulation of miR-221 and miR-222, which could hinder effective healing in periodontal treatments.
