Publications by authors named "Anna Buser"
Background: Young female athletes may have higher rates of overuse injuries and sport specialization than male athletes. The association of sports specialization and return to sport (RTS) timeframe is also unknown.
Hypothesis: Specialized female athletes will have more intense, year-round training patterns, more overuse injuries, and longer RTS times than male athletes.
Background: Overuse injuries in youth athletes are associated with risks, including sports specialization, biological maturation, female sex, and workload measures. As no assessment tool exists to evaluate risk accumulation, we developed a novel risk factor scoring system (Sport Training Assessment of Risk [STAR]) to assess participants' risk of overuse injury and explore association with return-to-play (RTP) time periods.
Hypothesis: (1) STAR will reach an acceptable predictive threshold in the assessment of overuse injury in youth athletes.
Article Synopsis
- - Proteus syndrome is a rare disorder causing overgrowth and related lung issues, and this study aims to analyze lung disease features using radiographic scoring systems: the Cystic Lung Score (CLS) and the Clinician Visual Score (CVS).
- - Data from 113 imaging studies of 44 patients showed that worsening CLS and CVS scores correlated with increased respiratory symptoms and decreased lung function, particularly affecting children more severely than adults.
- - The findings suggest that Proteus syndrome-related lung disease progresses over time, and both scoring methods effectively track these changes, which could inform future treatment and research efforts.
Proteus syndrome is a mosaic disorder that can cause progressive postnatal overgrowth of nearly any organ or tissue. To date, Proteus syndrome has been exclusively associated with the mosaic c.49G > A p.
View Article and Find Full Text PDFA dyadic genotype-phenotype approach to diagnostic criteria for Proteus syndrome.
Am J Med Genet C Semin Med Genet
December 2019
Phenotype-based diagnostic criteria were developed for Proteus syndrome in 1999 and updated in 2006. Subsequently, the causative mosaic gene alteration was discovered, the c.49G>A p.
View Article and Find Full Text PDFObjective: The purpose of this project was to use an in vivo method to discover riboswitches that are activated by new ligands. We employed phage-assisted continuous evolution (PACE) to evolve new riboswitches in vivo. We started with one translational riboswitch and one transcriptional riboswitch, both of which were activated by theophylline.
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