Multiple acyl-coenzyme A dehydrogenase deficiency shows a possible founder effect and is the most frequent cause of lipid storage myopathy in Iran.

Introduction: Multiple acyl-coenzyme A dehydrogenase deficiency disorder (MADD) is a relatively rare disorders of lipid metabolism. This study aimed to investigate the demographic, clinical, and genetic features of MADD in Iran.

Methods: Twenty-nine patients with a definite diagnosis of lipid storage myopathy were recruited.

Genetic heterogeneity of motor neuropathies.

Objective: To study the prevalence, molecular cause, and clinical presentation of hereditary motor neuropathies in a large cohort of patients from the North of England.

Methods: Detailed neurologic and electrophysiologic assessments and next-generation panel testing or whole exome sequencing were performed in 105 patients with clinical symptoms of distal hereditary motor neuropathy (dHMN, 64 patients), axonal motor neuropathy (motor Charcot-Marie-Tooth disease [CMT2], 16 patients), or complex neurologic disease predominantly affecting the motor nerves (hereditary motor neuropathy plus, 25 patients).

Results: The prevalence of dHMN is 2.

"God, why did this happen to me?": three perspectives on theodicy.

This article closely examines the way three people dealt with the theodicy question. The three study subjects participated in extended interviews about their religious beliefs and activities, past and present. The interviews were summarized and analyzed to identify the person's religious resources, statements about theodicy, and mental well-being.