Publications by authors named "Anna Beier"
Unlabelled: The generation of complex three-dimensional structures is a key developmental step for most eukaryotic organisms. The details of the molecular machinery controlling this step remain to be determined. An excellent model system to study this general process is the generation of three-dimensional fruiting bodies in filamentous fungi like Sordaria macrospora Fruiting body development is controlled by subunits of the highly conserved striatin-interacting phosphatase and kinase (STRIPAK) complex, which has been described in organisms ranging from yeasts to humans.
View Article and Find Full Text PDFThe striatin-interacting phosphatases and kinases (STRIPAK) complex is a highly conserved eukaryotic protein complex that was recently described for diverse animal and fungal species. Here, we summarize our current knowledge about the composition and function of the STRIPAK complex from the ascomycete Sordaria macrospora, which we discovered by investigating sexually sterile mutants (pro), having a defect in fruiting body development. Mass spectrometry and yeast two-hybrid analysis defined core subunits of the STRIPAK complex, which have structural homologs in animal and other fungal organisms.
View Article and Find Full Text PDFSymptomatic Lymphocele Formation After Sentinel Lymph Node Biopsy for Early Stage Cervical Cancer.
J Minim Invasive Gynecol
September 2016
In early stage cervical cancer, nodal status is the most important prognostic factor, and execution of retroperitoneal lymphadenectomy is currently an integral part of surgical therapy. Sentinel lymph node biopsy has been progressively incorporated with surgical therapy and could reduce morbidity. However, the current incidence of complications exclusively related to the procedure is unknown.
View Article and Find Full Text PDFArticle Synopsis
- This case report highlights a successful laparoscopic and fertility-preserving treatment for a rare ovarian cancer known as nongestational choriocarcinoma, with very few cases documented in the past decade.
- The patient, a 23-year-old woman, underwent a series of laparoscopic surgeries that included the removal of the affected tissue and thorough staging, ultimately confirming an advanced stage of the cancer (stage IIB).
- Post-surgery, she received chemotherapy and ovarian suppression, resulting in no recurrence of the cancer and a return to normal menstrual cycles after nine months, showcasing the potential of minimally invasive approaches in treating this malignancy while preserving fertility.