Publications by authors named "Anna A Kyselyova"
Purpose: Since perfusion imaging may be unavailable in smaller hospitals, alternative imaging selection methods for acute ischemic stroke can improve outcomes and optimize resources. This study assessed the safety and effectiveness of using imaging criteria other than DEFUSE 3 and DAWN for thrombectomy beyond 6 h from symptom onset in patients stroke in the anterior circulation.
Methods: This is a retrospective, single-center analysis of consecutive patients with large vessel occlusion in the anterior circulation undergoing thrombectomy.
Introduction: Managing blood pressure in patients with large vessel occlusion affects infarct size and clinical outcomes. We examined how restoring blood flow impacts systemic blood pressure during mechanical thrombectomy.
Patients And Methods: Patients with large vessel occlusion in the anterior circulation undergoing mechanical thrombectomy between June 2016 and January 2018 were screened.
Background And Purpose: Cerebral vasospasm is a common complication of aneurysmal SAH and remains a risk factor for delayed cerebral ischemia and poor outcome. The interrater reliability of CTA in combination with CTP has not been sufficiently studied. We aimed to investigate the reliability of CTA alone and in combination with CTP in the detection of cerebral vasospasm and the decision to initiate endovascular treatment.
View Article and Find Full Text PDFPurpose: Given the inherent complexity of neurointerventional procedures and the associated risks of ionizing radiation exposure, it is crucial to prioritize ongoing training and improve safety protocols. The aim of this study is to assess a training and evaluation environment using a vascular model of M1 stenosis, within a clinical angiography suite, without relying on animal models or X-ray radiation.
Materials And Methods: Using a transparent model replicating M1 stenosis, we conducted intracranial stenting procedures with four different setups (Gateway & Wingspan, Gateway & Enterprise, Neurospeed & Acclino, and Pharos Vitesse).
Article Synopsis
- - The study explores how imaging techniques, specifically "tissue clock" indicators like CT perfusion and net water uptake, can better predict early neurologic improvement in stroke patients receiving intravenous thrombolysis (IVT) than traditional time-based criteria.
- - Four hundred nine patients with strokes caused by proximal vessel occlusion were analyzed, revealing that IVT significantly improved early neurologic outcomes in those with low NWU or CTP mismatch, independent of the time since symptom onset.
- - The findings suggest that using CT-based "tissue clock" measures could more accurately identify patients who would benefit from IVT, potentially changing treatment approaches for stroke patients within extended time frames.
Purpose: Flow arrest using a balloon guide catheter (BGC) in mechanical thrombectomy (MT) due to large vessel occlusion has been associated with better outcomes. Known limitations of currently commercially available BGCs are incompatibility with large bore aspiration catheters (AC) and lack of distal flexibility. Walrus presents variable stiffness and compatibility with large bore AC.
View Article and Find Full Text PDFInterventional neuroradiology (INR) has not yet received official certification as a surgical subspecialty in Ukraine. Consequently, there is uncertainty surrounding the availability of a neurosurgical internship and a structured INR training program to provide neuroendovascular procedures. In recent years, mechanical thrombectomy has become the standard of care for acute ischemic stroke caused by large vessel occlusion, as supported by evidence-based guidelines.
View Article and Find Full Text PDFPurpose: The increased demand for training of mechanical thrombectomy in ischemic stroke and development of new recanalization devices urges the creation of new simulation models both for training and device assessment. Clots properties have shown to play a role in procedural planning and thrombectomy device effectiveness. In this study, we analyzed the characteristics and applicability of completely synthetic, animal-free clots in the setting of an in-vitro model of mechanical thrombectomy for training and device assessment.
View Article and Find Full Text PDFBackground: Mean kurtosis (MK), one of the parameters derived from diffusion kurtosis imaging (DKI), has shown increased sensitivity to tissue microstructure damage in several neurological disorders.
Methods: Thirty-seven patients with relapsing-remitting MS and eleven healthy controls (HC) received brain imaging on a 3T MR scanner, including a fast DKI sequence. MK and mean diffusivity (MD) were measured in the white matter of HC, normal-appearing white matter (NAWM) of MS patients, contrast-enhancing lesions (CE-L), FLAIR lesions (FLAIR-L) and black holes (BH).
Article Synopsis
- The study investigates the effectiveness of the ADAPT technique for thrombectomy, focusing on factors that influence successful clot aspiration in patients with certain types of artery occlusions.
- Researchers assessed data from 106 cases, evaluating various anatomical and clot characteristics such as vessel tortuosity, diameter, and patient age.
- Results indicate younger patients with less tortuous vessels achieved better catheter contact, while smaller vessel diameters and higher catheter-to-vessel ratios (CVR) were linked to more successful clot aspiration outcomes.