Publications by authors named "Ann-Christin Grimmelt"

Patients with interstitial lung disease due to surfactant protein C (SFTPC) mutations are rare and not well characterised. We report on all subjects collected over a 15-year period in the kids-lung register with interstitial lung disease and a proven SFTPC mutation. We analysed clinical courses, interventions and outcomes, as well as histopathological and radiological interrelations.

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Article Synopsis
  • A study aimed to identify factors that predict the long-term success of treatments to eliminate Pseudomonas aeruginosa in cystic fibrosis (CF) patients.
  • Researchers analyzed data from CF patients treated between 2005 and 2008, focusing on antibody responses one year post-treatment and their correlation with successful eradication three years later.
  • The results showed that specific antibodies could predict treatment outcomes, with a 75% positive and 82% negative predictive value for long-term success, as 60% of patients achieved successful eradication.
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Background: The relevance of Trichosporon species for cystic fibrosis (CF) patients has not yet been extensively investigated.

Methods: The clinical course of CF patients with Trichosporon spp. in their respiratory secretions was analysed between 2003 and 2010 in the Munich CF center.

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