Publications by authors named "Ann Shum"

Article Synopsis
  • * A study analyzed mucosal bacterial and fungal communities in 30 UC patients and found that butyrogenic bacteria, which produce butyrate, were significantly more abundant in quiescent mucosa compared to active mucosa.
  • * Higher fiber intake was positively linked to an increase in butyrogenic bacteria, suggesting that adjusting the mucosal microbiome to favor butyrate-producing bacteria could help maintain quiescence in UC patients.
View Article and Find Full Text PDF

Ozanimod is an oral sphingosine-1-phosphate receptor modulator. Although it can be an effective drug for the induction and maintenance of remission in patients with moderately to severely active ulcerative colitis, there have been a few reported cases of various malignancies after exposure to this small molecule. We describe a unique case of biopsy-proven Kaposi sarcoma of the skin and colon in a patient with biologic-resistant ulcerative colitis after treatment with ozanimod for 2 months.

View Article and Find Full Text PDF