Publications by authors named "Ann Q Tran"

Purpose: To demonstrate the role of Virtual Reality (VR) in orbital surgery as an educational tool for surgical trainees.

Methods: A single-center prospective study was conducted from February 2021 to April 2023. Pre-operative magnetic resonance imaging and computed tomography scans were used to create patient-specific VR models of the orbit using ImmersiveTouch Software.

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Purpose: To investigate the association between age and clinical activity score (CAS) in patients with active, untreated thyroid eye disease.

Methods: A retrospective review was conducted of patients with active, untreated thyroid eye disease at a single institution between 2010 and 2020 whose ophthalmologic symptoms began no more than 9 months prior to the initial visit. Exclusion criteria included surgical or systemic thyroid eye disease treatment before or during the study period.

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Article Synopsis
  • The study investigates whether specific components of ophthalmology residency applications can predict future performance of residents across multiple domains.
  • It involves a review of residency application materials and performance evaluations of graduates from 2006 to 2018 at seven U.S. ophthalmology residency programs.
  • Key findings indicate that higher USMLE Step 1 scores, honors in core clerkships, and membership in medical honor societies are strongly associated with better performance in clinical, surgical, academic, and overall categories.
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  • Open imaging fluorescence devices using indocyanine green (ICG) have been tested in surgical procedures related to the periorbital area to visualize blood flow and lymphatic drainage.
  • A prospective study conducted from 2021 to 2022 involved 22 patients for ICG angiography and 10 for ICG lymphangiography, successfully showing the vascular supply and lymphatic systems in various surgical contexts.
  • The findings demonstrated that ICG is effective in assessing blood circulation in ocular surgeries and understanding lymphatic pathways, improving surgical outcomes and patient care.
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  • A 42-year-old woman, not experiencing menopause and not pregnant, discovered a lesion in her right orbital apex that was causing mild optic nerve compression.
  • Imaging indicated that the mass was likely a cavernous venous malformation displacing the optic nerve.
  • Over 15 years of monitoring with regular imaging and exams, the lesion significantly shrank, and the optic neuropathy completely resolved.
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Purpose: To determine treatment outcomes, recurrence rates, and predictors of recurrence, to inform future therapeutic approaches for spheno-orbital meningiomas (SOM).

Methods: A retrospective single-center study of SOM treated from 1990 to 2021 was conducted with comprehensive neuro-ophthalmologic follow-up at Columbia University Medical Center (CUMC). Recurrence requiring reintervention was defined clinically as worsening of visual acuity, visual field defect, or ocular motility after an initial period of stabilization or 6 months of improvement following treatment, or radiologically as either a regrowth with an increase in tumor size by 20% at the site of previous growth or a new region of tumor growth.

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A 72-year-old woman with a history of chronic cocaine use presented 9 months after a dog bite with a large facial ulceration and absent sinonasal structures. Biopsies were negative for infectious, vasculitic, or neoplastic pathologies. The patient was lost to follow up for 15 months and returned with a significantly larger lesion despite abstinence from cocaine.

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  • Middle turbinate resection (MTR) is a surgical procedure often done alongside endonasal sinus surgeries, particularly to enhance the medial orbital wall decompression process.
  • This study examined the effects of MTR on orbital soft-tissue volume, utilizing imaging software to compare pre- and post-surgery CT scans of patients who underwent this procedure.
  • Among five female patients with hyperthyroidism, the results showed that MTR led to an average increase of 0.83 cc in orbital soft tissue volume without any postoperative complications, suggesting its effectiveness in improving surgical outcomes.
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Purpose: The purpose of this study was to describe the clinical characteristics, management, and outcomes of orbital blow-in fractures involving compression of the globe by bone fragments.

Methods: A retrospective case series and systematic literature review were performed.

Results: Three male patients (mean age 29 years) with orbital blow-in fractures causing globe indentation presented with extraocular movement restriction, choroidal folds, and B-scan ultrasonography demonstrating deformation of the globe contour by a hyperechoic bone fragment.

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Purpose: The aim of this study was to characterize major topics of discussion in oculoplastic surgery on a social media forum and to evaluate the medical accuracy of the content discussed on these platforms.

Methods: A cross-sectional analysis of oculoplastics key search terms was performed on 2 active forums (r/PlasticSurgery and r/CosmeticSurgery) on Reddit. The content analysis involved the top posts in Reddit's history from 2008 to 2022.

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  • A 67-year-old man with multiple health issues experienced severe left eye problems, including orbital pain and vision loss, and was diagnosed with left orbital apex syndrome with optic nerve involvement.
  • The MRI showed significant changes in the optic nerve and surrounding areas, but initial treatments and tests yielded no conclusive results.
  • Five months later, he returned with new symptoms, and further imaging revealed a high-grade glioblastoma affecting both optic nerves and the suprasellar region, highlighting the importance of molecular profiling for better diagnosis and potential treatments.
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Purpose: To assess the evolution of proptosis asymmetry during the active phase of bilateral thyroid eye disease (TED).

Methods: A retrospective study was conducted on patients with bilateral, active TED. Patients were measured by a single observer, using Hertel exophthalmometry from the time of initial presentation, during the active phase of TED, to the stable phase, 24-months later.

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Purpose: The purpose of this study was to characterize intradiploic dermoid and epidermoid orbital cysts to determine any differences in clinical, radiographic, or surgical features.

Methods: A retrospective review was performed of patients presenting with intradiplopic dermoid or epidermoid cysts. Additionally, a complete review of the literature was performed to identify cases of intradiplopic orbital dermoid and epidermoid cysts.

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Purpose: To morphologically describe and mathematically quantify a novel clinical feature of thyroid eye disease (TED).

Methods: A retrospective study was conducted of TED patients and age-sex-matched normal controls. The arched Rainbow Brow appearance in TED patients was determined by unanimous agreement of 3 oculoplastic surgeons.

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Purpose: To examine the clinical and histopathologic characteristics of lacrimal gland biopsies at a tertiary academic center.

Methods: A retrospective chart review of patients undergoing lacrimal gland biopsy or excision between 1962 and 2017 was performed via the ocular pathology specimen log. All cases were reviewed for demographics, clinical presentation, and histopathologic diagnoses.

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The aim of the study is to describe a mathematical model for analyzing eyebrow curvature that can be applied broadly to curvilinear facial features. A total of 100 digital images (50 men, 50 women) were obtained from standardized headshots of medical professionals. Images were analyzed in ImageJ by plotting either 8 or 15 points along the inferior-most row of contiguous brow cilia.

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