Serial audiometry in a clinical trial of AIED treatment.

Objective: We analyzed pure-tone and speech audiometric results from a prospective trial of anti-inflammatory treatment of subjects with active autoimmune inner ear disease (AIED). We sought to characterize the pattern and size of the treatment effect as reflected in clinical audiometry and to identify audiometric predictors of response to steroid treatment of AIED.

Subjects: Adult participants demonstrated clinically established criteria for AIED (n = 116).

Improved speech perception in adult congenitally deafened cochlear implant recipients.

Objective: To determine whether congenitally deafened adults achieve improved speech perception when auditory and visual speech information is available after cochlear implantation.

Study Design: Repeated-measures single subject analysis of speech perception in visual-alone, auditory-alone, and audiovisual conditions.

Setting: Neurotologic private practice and research institute.

Hearing changes after diagnosis in neurofibromatosis type 2.

Objective: Describe the changes in hearing ability and progression of disease over time in subjects with neurofibromatosis Type 2 enrolled in a multicenter natural history study of vestibular schwannomas in neurofibromatosis Type 2.

Study Design: Retrospective clinical study.

Setting: International neurofibromatosis Type 2 tertiary care centers.