Publications by authors named "Ann M O'Hare"

Importance: Transplant can be a valuable treatment option for older adults with kidney failure, and recent initiatives encourage more frequent referral to transplant centers. However, the evaluation process can be challenging, and most older adults do not ultimately receive a kidney.

Objective: To elucidate the perspectives and experiences of older adults with advanced kidney disease and their family members regarding the kidney transplant evaluation process.

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  • A study investigates whether COVID-19 is linked to long-term financial hardships among Veterans, particularly those enrolled in the Veterans Health Administration, finding that many face challenges even 18 months post-infection.
  • The research involved a survey of 194 Veterans with a history of COVID-19 and 194 Veterans without, measuring various financial strains and hardships related to health costs and material needs.
  • Results show that 67% of participants experienced financial hardship, with COVID-19 infected Veterans being at significantly higher risk for severe financial strain compared to their uninfected counterparts.
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  • Older adults with kidney failure not referred for transplant have two options: starting dialysis or continuing medical management, which may prolong home time and survival.
  • An observational study compared survival and time spent at home between groups starting dialysis and those opting for medical management, revealing only slight differences in survival (9.3 days) with the dialysis group having 13.6 fewer days at home.
  • Limitations of the study include potential unmeasured confounding and limited applicability to women and non-veterans, suggesting cautious interpretation of the results for broader populations.
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Geographic variation in hardship, especially health-related hardship, was identified prior to and during the pandemic, but we do not know whether this variation is consistent among Veterans Health Administration (VHA)-enrolled veterans, who reported markedly high rates of financial hardship during the pandemic, despite general and veteran-specific federal policy efforts aimed at reducing hardship. In a nationwide, regionally stratified sample of VHA-enrolled veterans, we examined whether the prevalence of financial hardship during the pandemic varied by US Census region. We found veterans in the South, compared with those in other census regions, reported higher rates of severe-to-extreme financial strain, using up all or most of their savings, being unable to pay for necessities, being contacted by collections, and changing their employment due to the kind of work they could perform.

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Rationale & Objective: Developing strategies to improve home dialysis use requires a comprehensive understanding of barriers. We sought to identify the most important barriers to home dialysis use from the perspective of patients, care partners, and providers.

Study Design: This is a convergent parallel mixed-methods study.

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  • Research shows that SARS-COV-2 infection can lead to increased depression symptoms, particularly among veterans who often have pre-existing mental and physical health issues.
  • This study aimed to investigate the specific link between SARS-COV-2 infection and depression in U.S. Military Veterans, filtering out other contributing factors.
  • Results indicated that veterans who contracted SARS-COV-2 exhibited significantly higher levels of depression symptoms, particularly psychological indicators like low mood and suicidal thoughts, compared to those who did not get infected.
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Importance: Research demonstrates that SARS-CoV-2 infection is associated with increased risk of all-cause hospitalization. However, no prior studies have assessed the association between SARS-CoV-2 and potentially preventable hospitalizations-that is, hospitalizations for conditions that can usually be effectively managed in ambulatory care settings.

Objective: To examine whether SARS-CoV-2 is associated with potentially preventable hospitalization in a nationwide cohort of US veterans.

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  • This study investigates how COVID-19 infection affects daily functioning of veterans 18 months after infection, comparing those who had COVID-19 with those who didn't.
  • It analyzed data from 186 veterans with COVID-19 and 186 matched veterans without the infection, examining various factors to ensure a fair comparison.
  • Results showed that 44.9% of veterans who had COVID-19 reported diminished capabilities in daily activities compared to 35.3% of those in the control group, highlighting the lasting impact of the virus.
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  • The study found that most dialysis patients and doctors in Japan support starting discussions about advance care planning early, particularly when dialysis begins.
  • Despite this preference, only 11% of the surveyed patients had actually engaged in such discussions with their clinicians.
  • The research highlights a significant gap between the desire for proactive planning and the current practice regarding advance care discussions in dialysis care.
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  • - The study aimed to investigate how COVID-19 infection impacted outpatient healthcare utilization among veterans, comparing those infected with those who were not across various care categories.
  • - It analyzed data from a large cohort of matched veterans using records from Veterans Affairs and Medicare, focusing on outpatient visits pre- and post-COVID infection over a year.
  • - Results showed that veterans with COVID-19 had significantly more outpatient visits (especially in primary care) during the peri-infection period compared to uninfected veterans, with a notable increase of 5.12 additional visits per 30 days.
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Importance: A significant proportion of SARS-CoV-2 infected individuals experience post-COVID-19 condition months after initial infection.

Objective: To determine the rates, clinical setting, risk factors, and symptoms associated with the documentation of International Statistical Classification of Diseases Tenth Revision (ICD-10), code U09.9 for post-COVID-19 condition after acute infection.

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Importance: Despite growing evidence of persistent problems after acute COVID-19, how long the excess mortality risk associated with COVID-19 persists is unknown.

Objective: To measure the time course of differential mortality among Veterans who had a first-documented COVID-19 infection by separately assessing acute mortality from later mortality among matched groups with infected and uninfected individuals who survived and were uncensored at the start of each period.

Design, Settings, And Participants: This retrospective cohort study used prospectively collected health record data from Veterans Affairs hospitals across the US on Veterans who had COVID-19 between March 2020 and April 2021.

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Reliable transportation is an important determinant of access to health care and health outcomes that carries particular significance for people with ESKD. In the United States, there are almost half a million patients receiving treatment with in-center dialysis, translating into more than 70 million roundtrips to dialysis centers annually. Difficulty with transportation can interfere with patients' quality of life and contribute to missed or shortened dialysis treatments, increasing their risk for hospitalization.

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Importance: The second year of the COVID-19 pandemic saw periods of dire health care resource limitations in the US, sometimes prompting official declarations of crisis, but little is known about how these conditions were experienced by frontline clinicians.

Objective: To describe the experiences of US clinicians practicing under conditions of extreme resource limitation during the second year of the pandemic.

Design, Setting, And Participants: This qualitative inductive thematic analysis was based on interviews with physicians and nurses providing direct patient care at US health care institutions during the COVID-19 pandemic.

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Ethnographic research with cognitively impaired older adults can be challenging, in part because cognitive impairment raises questions about the ability to provide informed consent. Relying on proxy consent is a commonly used strategy, but often excludes people with dementia who lack close kin (de Medeiros, Girling, & Berlinger, 2022). In this paper, we describe how we have analyzed existing research data from a well-established and ongoing prospective cohort study, the Adult Changes in Thought Study, along with unstructured text from the medical records of participants who had no living spouse or adult children when they developed dementia, as a way of studying the circumstances, life trajectories, caregiving resources, and care needs of this vulnerable and difficult-to-research group.

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Objectives: To determine the association between covid-19 vaccination types and doses with adverse outcomes of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection during the periods of delta (B.1.617.

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Background: Understanding how SARS-CoV-2 infection impacts long-term patient outcomes requires identification of comparable persons with and without infection. We report the design and implementation of a matching strategy employed by the Department of Veterans Affairs' (VA) COVID-19 Observational Research Collaboratory (CORC) to develop comparable cohorts of SARS-CoV-2 infected and uninfected persons for the purpose of inferring potential causative long-term adverse effects of SARS-CoV-2 infection in the Veteran population.

Methods: In a retrospective cohort study, we identified VA health care system patients who were and were not infected with SARS-CoV-2 on a rolling monthly basis.

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Importance: Patients receiving maintenance dialysis experience intensive patterns of end-of-life care that might not be consistent with their values.

Objective: To evaluate the association of patients' health care values with engagement in advance care planning and end-of-life care.

Design, Setting, And Participants: Survey study of patients who received maintenance dialysis between 2015 and 2018 at dialysis centers in the greater metropolitan areas of Seattle, Washington, and Nashville, Tennessee, with longitudinal follow-up of decedents.

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