Habituation is one of the oldest forms of learning, broadly expressed across sensory systems and taxa. Here, we demonstrate that olfactory habituation induced at different timescales (comprising different odor exposure and intertrial interval durations) is mediated by different neural mechanisms. First, the persistence of habituation memory is greater when mice are habituated on longer timescales.
View Article and Find Full Text PDFFish in the family Mormyridae produce weak electric organ discharges that are used in orientation and communication. The peripheral and central anatomy of the electrosensory system has been well studied in the species Gnathonemus petersii, but comparative studies in other species are scarce. Here we report on one genus of mormyrid that displays a remarkable change in the electrosensory lateral line lobe (ELL), the hypertrophied rhombencephalic structure that receives primary electroreceptor input.
View Article and Find Full Text PDFPurpose: To use evidence-based techniques to compare elective open surgical repair of abdominal aortic aneurysms with endovascular repair by means of stent placement.
Materials And Methods: A focused clinical question formed the basis of a literature search. Evidence-based criteria were used to appraise and assign a "level of evidence" to retrieved articles.
Ear Nose Throat J
December 2002
We attempted to determine if women younger than 45 years of age who have isolated papillary thyroid cancer and whose tumors are smaller than 4 cm (T2N0M0) are at low risk for mortality and morbidity following thyroid lobectomy. To this end, we analyzed information on both women and men obtained from our review of the literature, and we integrated it with data compiled in the Delaware Cancer Registry. We performed a secondary analysis to determine if the risk of death and recurrence can be predicted on the basis of age, tumor size, sex, histology, and the type of operation.
View Article and Find Full Text PDFA ground beef patty processor detected Escherichia coli O157:H7 in five production lots during routine testing with polymerase chain reaction (PCR) technology. This finding stimulated research to determine the incidence and potential entry points of the pathogen during processing. One of these lots (53,960 kg) was divided into 71 pallets (760 kg each) of food service ground beef patties.
View Article and Find Full Text PDFPharmacoepidemiol Drug Saf
June 2002
Purpose: To examine use of chronic therapies by females and males of all ages.
Methods: Participants were 1,295,948 members of a large US pharmacy benefit manager. The use of chronic medications by males and females during 1999 was examined overall and within 16 commonly-used chronic drug groups.
Objective: To report the top 15 prescription drug categories used by males and females of all ages and to compare this information with national prevalence data.
Methods: Data used were pharmacy claim and eligibility information over the period January 1, 1999, through December 31, 1999, for 1,294,295 members of a large pharmacy benefit manager. Participant ages ranged from 1 to more than 100 years.