Publications by authors named "Ann Kristin Knudsen"

Aim: In the context of mortality, heart failure (HF) represents an intermediate factor and should not be used to describe underlying cause of death (UCoD). We explored the potential educational gradients in use of HF to describe UCoD using national data spanning more than 30 years from Norway.

Methods: Using a cross-sectional design, we linked data from the Cause of Death Registry and the National Education Database.

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Aim: The inclusion of production losses in health care priority setting is extensively debated. However, few studies allow for a comparison of these losses across relevant clinical and demographic categories. Our objective was to provide comprehensive estimates of Norwegian production losses from morbidity and mortality by age, sex and disease category.

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Background: Norway is a high-income nation with universal tax-financed health care and among the highest per person health spending in the world. This study estimates Norwegian health expenditures by health condition, age, and sex, and compares it with disability-adjusted life-years (DALYs).

Methods: Government budgets, reimbursement databases, patient registries, and prescription databases were combined to estimate spending for 144 health conditions, 38 age and sex groups, and eight types of care (GPs; physiotherapists & chiropractors; specialized outpatient; day patient; inpatient; prescription drugs; home-based care; and nursing homes) totaling 174,157,766 encounters.

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Background: Register-based studies of major depressive disorder (MDD) do not capture all prevalent cases, as untreated cases and diagnoses made by general practitioners are not recorded in the registers. We examined the prevalence and agreement of survey- and register-based measures of depression, and explored sociodemographic and health-related factors that may have influenced this agreement.

Methods: All 32,407 participants in the 2017 Central Denmark Region How are you? survey were linked to hospital and prescription records.

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Objective: To investigate the associations between low education and risk of mental disorders, substance use disorders and self-harm in different age-groups.

Methods: All subjects in Stockholm born between 1931 and 1990 were linked to their own or their parent's highest education in 2000 and followed-up for these disorders in health care registers 2001-2016. Subjects were stratified into four age-groups: 10-18, 19-27, 28-50, and 51-70 years.

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Background: Mental disorders can affect workforce participation via a range of mechanisms. In this study, we aimed to estimate the association between different types of mental disorders and working years lost, defined as the number of years not actively working or enrolled in an educational programme.

Methods: In this population-based cohort study, we included all people aged 18-65 years (mean 38·0 [SD 13·9]) in the Danish Civil Registration System from Jan 1, 1995 to Dec 31, 2016.

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Background: Calculating the disease burden due to injury is complex, as it requires many methodological choices. Until now, an overview of the methodological design choices that have been made in burden of disease (BoD) studies in injury populations is not available. The aim of this systematic literature review was to identify existing injury BoD studies undertaken across Europe and to comprehensively review the methodological design choices and assumption parameters that have been made to calculate years of life lost (YLL) and years lived with disability (YLD) in these studies.

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Social media (SOME) use among adolescents has been linked to mental health and well-being. SOME self-presentation has been highlighted as an important factor to better understand the potential links. The aims of this study were to investigate the association between focus on SOME self-presentation and mental health and quality of life among adolescents.

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Introduction And Aims: The gender difference in alcohol use seems to have narrowed in the Nordic countries, but it is not clear to what extent this may have affected differences in levels of harm. We compared gender differences in all-cause and cause-specific alcohol-attributed disease burden, as measured by disability-adjusted life-years (DALY), in four Nordic countries in 2000-2017, to find out if gender gaps in DALYs had narrowed.

Design And Methods: Alcohol-attributed disease burden by DALYs per 100 000 population with 95% uncertainty intervals were extracted from the Global Burden of Disease database.

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Article Synopsis
  • A study examined trends in psychological distress among Norwegian college students from 2010 to 2018, using data from a nationwide survey called the Students' Health and Wellbeing Study (SHoT).
  • Results showed a significant increase in self-reported psychological distress, particularly among women, with their HSCL-25 scores rising from 1.62 to 1.82 over the study period.
  • The findings raise concerns about the mental wellbeing of students, highlighting the need for further investigation into the causes of this distress, while also noting the study's low participation rates may affect the reliability of the results.
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Importance: Examining causes of death and making comparisons across countries may increase understanding of the income-related differences in life expectancy.

Objectives: To describe income-related differences in life expectancy and causes of death in Norway and to compare those differences with US estimates.

Design And Setting: A registry-based study including all Norwegian residents aged at least 40 years from 2005 to 2015.

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Bakgrunn: For å kunne møte helseutfordringer i befolkningen trenger vi oversikt over befolkningens helsetilstand. I Norge har vi tradisjonelt hatt god oversikt over dødsårsaker, men vi vet mindre om byrden fra tilstander som medfører sykelighet, såkalt ikke-dødelig helsetap. Vårt mål var å beskrive den totale sykdomsbyrden i Norge i 2016, utviklingen de siste ti årene samt kjønnsforskjeller i sykdomsbyrde.

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Article Synopsis
  • Mental disorders frequently begin early in life and significantly impact young adults' ability to carry out developmental tasks, but there's limited understanding of mental disorder prevalence and progression into young adulthood.
  • A study assessing young adult Norwegian twins found that the prevalence of any mental disorder in their twenties was 19.8% for men and 32.4% for women, with notable rates for specific disorders such as anxiety and major depressive disorder (MDD).
  • The study revealed that while mental disorder prevalence decreases from the twenties to the thirties/forties, individuals with mental disorders in their twenties are at a higher risk of experiencing similar disorders a decade later, indicating lasting effects on their personal and professional development.
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Aims: Economic gender equality is one of the goals of the Nordic Welfare states. Despite this, there is a considerable gender gap in pensionable income in the European Union, and an unmet need for measures that absorb more of the complexity associated with accumulated (dis)advantages across gender and population groups. The aims of the present study were to examine the gender difference in association between average earned pension points and 1) education and 2) current occupational prestige, and to discuss pension points as a possible indicator of accumulated disadvantages.

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Objectives: We used findings from the Global Burden of Disease Study 2013 to report the burden of musculoskeletal disorders in the Eastern Mediterranean Region (EMR).

Methods: The burden of musculoskeletal disorders was calculated for the EMR's 22 countries between 1990 and 2013. A systematic analysis was performed on mortality and morbidity data to estimate prevalence, death, years of live lost, years lived with disability and disability-adjusted life years (DALYs).

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The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental disorders in the EMR.

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Background: The risk of ischaemic heart disease (IHD) is largely influenced by lifestyle. Interestingly, cohort studies show that anxiety in general is associated with increased risk of IHD, independent of established risk factors for cardiovascular disease. Health anxiety is a specific type of anxiety characterised by preoccupation of having, acquiring or possibly avoiding illness, yet little is known about lifestyle and risk of disease development in this group.

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Aims: (1) To compare alcohol-attributed disease burden in four Nordic countries 1990-2013, by overall disability-adjusted life years (DALYs) and separated by premature mortality [years of life lost (YLL)] and health loss to non-fatal conditions [years lived with disability (YLD)]; (2) to examine whether changes in alcohol consumption informs alcohol-attributed disease burden; and (3) to compare the distribution of disease burden separated by causes.

Design: A comparative risk assessment approach.

Setting: Sweden, Norway, Denmark and Finland.

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Introduction And Aims: Adolescence is a period in which many have an onset of alcohol use, but there is much heterogeneity in the individual development of alcohol use. Further, there is a general increase in depressive symptoms from early to late adolescence, but less is known about how different alcohol habit trajectories are associated with symptoms of depression. The aims of the present study were: to identify trajectories of alcohol consumption and drinking to intoxication during adolescence (age 13-18 years); and examine to what extent the different trajectories of alcohol use were associated with symptoms of depression over the same age span, from early to late adolescence.

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Background: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for prevention. The GBD 2013 provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution.

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Background: The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age-sex groups, and countries. The GBD can be used to generate summary measures such as disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) that make possible comparative assessments of broad epidemiological patterns across countries and time. These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development.

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Background: Persons with diabetes have increased risk of depression, however, studies addressing whether the risk varies by age and type of antidiabetic treatment have yielded conflicting results. The aim of this study was to investigate if the association between diabetes and depression varied by type of antidiabetic treatment in a large community based sample of middle-aged (40-47 years) and older adults (70-72 years).

Methods: Data from 21845 participants in the Hordaland Health Study (HUSK) were analyzed in a cross-sectional design.

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Background: Uncertainty exists with regards to the extent of prevalence and health care use for musculoskeletal disorders in Norway. The aim of this study was to estimate the prevalence of chronic musculoskeletal disorders and to estimate the prevalence of persons receiving primary and specialist health services for these disorders.

Methods: We used three data-sources.

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Background: Dementia is an increasing public health challenge, and the number of individuals affected is growing rapidly. Mental disorders and symptoms of mental distress have been reported to be risk factors for dementia. The aim of this study was to examine whether midlife mental distress is a predictor for onset of dementia later in life.

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Background: Aggregated measures are often employed when prevalence, risk factors and consequences of alcohol use in the population are monitored. In order to avoid time-dependent bias in aggregated measures, reference periods which assess alcohol use over longer time-periods or measures assessing typical alcohol use are considered superior to reference periods assessing recent or current alcohol consumption. Alcohol consumption in the population is found to vary through the months of the year, but it is not known whether monthly variations in actual alcohol use affects self-reports of long-term or typical alcohol consumption.

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