Publications by authors named "Ann Jenkins"
Our aim was to evaluate the safety of transplanting kidneys from HCV-infected donors in HCV-uninfected recipients. Data collected from 53 recipients in a single center, observational study included donor and recipient characteristics, liver and kidney graft function, new infections and de novo donor-specific antibodies and renal histology. Treatment with a direct-acting antiviral regimen was initiated when HCV RNA was detected.
View Article and Find Full Text PDFKnowledge management plays a critical role in global health. Global health practitioners require knowledge in every aspect of their jobs, and in resource-scarce contexts, practitioners must be able to rely on a knowledge management system to access the latest research and practice to ensure the highest quality of care. However, we suggest that there is a gap in the way knowledge management is primarily utilized in global health, namely, the systematic incorporation of human and social factors.
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- The study investigates how immune cells, specifically dendritic cell (DC) precursors, contribute to tumor growth and blood vessel formation (vasculogenesis) in cancer.
- Researchers found that a protein called beta-defensin-29 attracts DC precursors to tumors, which enhances tumor blood supply and growth, especially when the tumor also produces vascular endothelial growth factor-A (Vegf-A).
- A new type of leukocyte expressing markers from both DCs and blood vessels was identified in ovarian tumors, and it was shown that these DCs not only migrate to tumor vessels but also help form new blood vessels, highlighting the cooperative roles of beta-defensins and Vegf-A in this process.