Treatment of vasodepressor carotid sinus syndrome with midodrine: a randomized, controlled pilot study.

Objectives: To evaluate the efficacy of treatment of the vasodepressor form of carotid sinus hypersensitivity (carotid sinus syndrome (CSS)) with midodrine.

Design: A prospective, double-blind, randomized, controlled trial of crossover design.

Setting: A dedicated outpatient facility with access to tilt-table, digital arterial photoplethysmography, and 24-hour ambulatory blood pressure (BP) monitoring equipment.