Background: Testicular function, including compensated Leydig cell function, has been indicated to be an early marker of morbidity.
Objective: To study the association of testicular function and markers of metabolic and cardiovascular health in a population of young men.
Materials And Methods: A cross-sectional study of 2289 men (median age 19 years, 5-95 percentile 18.
Andrology
November 2021
Background: Infertility affects 15%-25% of all couples during their reproductive life span. It is a significant societal and public health problem with potential psychological, social, and economic consequences. Furthermore, infertility has been linked to adverse long-term health outcomes.
View Article and Find Full Text PDFStudy Question: Is there a difference in testicular function in early adulthood between men born with cryptorchidism and men born with normally descended testes?
Summary Answer: In men from the general population, a history of cryptorchidism was associated with lower total testis volume and impaired semen quality as well as altered serum levels of reproductive hormones.
What Is Known Already: The association between cryptorchidism and testicular function is well documented in studies based on sub-fertile or infertile men recruited from a clinical setting. However, the association has not previously been investigated in men from the general population, who were unselected regarding fertility status.