Publications by authors named "Anlan Liu"
Liangxue Tongyu Prescription (LTP) is a classic herbal formula for treating acute intracerebral hemorrhage (AICH) in China. Previous studies have shown that LTP significantly ameliorates neurological impairments and gastrointestinal dysfunction in patients with AICH. However, the underlying molecular mechanism remains unclear.
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- * LTP was found to decrease levels of pro-inflammatory cytokines and prevent microglial activation, suggesting a protective role against inflammatory damage in the brain following AICH.
- * The research implies that LTP may work through the gut-brain axis by increasing cholecystokinin octapeptide (CCK-8) levels and altering expressions of key proteins in both the brain and intestine, thereby mitigating neuroinflammation.
Chaihu-jia-Longgu-Muli-tang (CLM) is derived from "Shang Han Lun" and is traditionally prescribed for treating depression. However, there is still a lack of evidence for its antidepressant effects, and the underlying mechanism is also unclear. This study aimed to assess clinical evidence on the efficacy of CLM in patients with depression using a meta-analysis and to explore its underlying antidepressant molecular mechanisms via network pharmacology.
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