Publications by authors named "Ankur Saharan"
Article Synopsis
- Male infertility accounts for about 40% of infertility cases, with High Sperm DNA Fragmentation (SDF) being a significant contributor, affecting natural conception and assisted reproductive technology (ART) outcomes.
- SDF is mainly caused by factors such as apoptosis, protamination failure, and excessive reactive oxygen species, highlighting the limitations of traditional infertility tests for men with normal sperm counts.
- Various testing and treatment strategies have been developed over the last 25 years to diagnose and reduce DNA fragmentation, aiming to improve sperm quality and enhance success rates in assisted reproduction.
Individuals with inflammatory bowel disease (IBD) have been reported to be at an increased risk of infertility and sexual dysfunction. Although the relationship between them remains unclear, IBD severity is suspected to affect hormone levels and fertility. To analyze the impact of IBD severity on semen parameters and sex hormone levels in ulcerative colitis-type IBD (UC-IBD), we conducted a cross-sectional study involving 120 patients with UC-IBD in Adam Malik General Hospital, Medan, Indonesia.
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