Serum galactomannan in histoplasmosis in HIV.

Histoplasmosis is an opportunistic infection (OI) in HIV infected patients. The Diagnosis is challenging due to lack of testing facilities. Hereby we report a young male who presented with fever & rash, was diagnosed with HIV and disseminated histoplasmosis.

Tiger Man Sign-F-18 FDG PET CT Scan Pattern in Muscular and Cutaneous Sarcoidosis: A Case Report and Literature Survey.

Sarcoidosis is a chronic granulomatous disorder of unknown etiology which primarily affects the respiratory system. However, 0.5%-2.

Clinical Significance of Retrograde Inferior Vena Cava and Hepatic Vein Opacification during Contrast Enhanced Tri-Phasic CT Abdomen Acquired as Part of F-18 FDG PET CT Scan - Learning Point For Nuclear Medicine Physicians: A Case Report and Literature Survey.

Hepatic veins and inferior vena cava are opacified during the delayed venous phase on triphasic contrast-enhanced computed tomography (CECT) abdomen scan. However, their early opacification/visualization in the arterial phase is usually due to retrograde flow of intravenous contrast from the right atrium in patients with right-sided heart failure or right ventricular dysfunction. Awareness and recognition of this phenomenon is important for nuclear medicine physicians reporting F18 fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET CT) scan with diagnostic CECT.

Localization and restaging of carcinoma prostate by Gallium prostate-specific membrane antigen positron emission tomography computed tomography in patients with biochemical recurrence.

Introduction: Radical prostatectomy (RP) and radical radiotherapy (RT) are well established primary curative options for localized prostate cancer. Despite technical improvements, prostate-specific antigen (PSA)-recurrence after RP and RT is a common clinical scenario. We aimed to assess the role of Gallium (Ga) prostate-specific membrane antigen positron emission tomography computed tomography (PSMA PET/CT) in patients with biochemical recurrence of prostate cancer after RP or RT for the detection and localization recurrent and metastatic disease.

An unusual case of hyperparathyroidism, presenting as multiple skeletal lesions.

We report the case of a 43-year-old male patient, who presented with severe osteoporosis and pain at multiple sites and a chest X-ray suggestive of few cystic lesions in bilateral ribs. Subsequently, the patient was referred for bone scan, in view of the suspicion of polyostotic fibrous dysplasia or neoplastic lesions. Bone scan showed homogenously increased tracer uptake in the axial and appendicular skeletal system, suggestive of metabolic superscan.

Fibrodysplasia Ossificans Progressiva - A Rare Genetic Disorder and the Role of Technetium-99m Methylene Diphosphonate Bone Scan.

Fibrodysplasia ossificans progressiva is a rare genetic disease believed to occur in approximately 1 in 2 million people worldwide and is characterized by progressive extraosseous ossification over the course of a lifetime in an inevitable and unpredictable episodic manner, with most patients being confined to a wheelchair by the third decade of life and requiring life-long care. The extraosseous calcification involves ligaments, tendons, muscles, and connective tissue leading to severe restriction of movements. Another hallmark of this condition is abnormal great toes.

Ga-68 DOTANOC PET/CT imaging in detection of primary site in patients with metastatic neuroendocrine tumours of unknown origin and its impact on clinical decision making: experience from a tertiary care centre in India.

Background: Neuroendocrine tumours (NETs) are rare, heterogeneous group of tumours which usually originate from small, occult primary sites and are characterized by over-expression of somatostatin receptors (SSTRs). Positron emission tomography/computed tomography (PET/CT) using Ga-68-labeled-somatostatin-analogues have shown superiority over other modalities for imaging of NETs. The objective of the study was to retrospectively evaluate the efficacy of Ga-68 DOTANOC PET/CT imaging in detecting the primary site in patients with metastatic NETs of unknown origin and its impact on clinical decision making in such patients.

Does the intensity of diffuse thyroid gland uptake on F-18 fluorodeoxyglucose positron emission tomography/computed tomography scan predict the severity of hypothyroidism? Correlation between maximal standardized uptake value and serum thyroid stimulating hormone levels.

Context: F-18 fluorodeoxyglucose (F-18 FDG) positron emission tomography/computed tomography (PET/CT) scan and hypothyroidism.

Aims: The aim was to determine whether the intensity of diffuse thyroid gland uptake on F-18 FDG PET/CT scans predicts the severity of hypothyroidism.

Materials And Methods: A retrospective analysis of 3868 patients who underwent F-18 FDG PET/CT scans, between October 2012 and June 2013 in our institution for various oncological indications was done.

Solitary spinal epidural metastasis from lung carcinoma.

Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has revealed many unusual presentations and early detection of metastasis in many carcinomas. Epidural involvement in the spine is mostly sequelae of direct infiltration from bony involvement. Direct hematogenous spread to epidural space is very rare.

Incidentally detected arterial thrombosis in (99m)Tc-methylene diphosphonate skeletal scintigraphy: an atypical observation.

The association between cancer and venous thrombosis is well established. However, that between malignancy and arterial thrombosis is less well described. We herein report a 48-year-old male patient diagnosed with base of tongue carcinoma, referred for Tc-methylene diphosphonate (MDP) bone scan study to evaluate recently developed pain and numbness in his right leg while undergoing chemoradiation.

Quantitative analysis of SPECT imaging parameters in patients with resting perfusion defects on myocardial perfusion scintigraphy.

Background: Functional status/contractile behaviour of hibernating myocardium was analyzed objectively by analyzing the available quantitative parameters obtained on gated SPECT myocardial perfusion imaging (MPI) using Emory cardiac toolbox (ECTB) software.

Materials And Methods: In this retrospective study, 70 patients with perfusion defects on (99)Tc-Sestamibi MPI (12 females, 58 males) who also underwent (18)F-FDG Cardiac PET study for assessment of hibernating myocardium were included for analysis. Patients were divided in three categories based on summed rest score (SRS) obtained from ECTB software, depicting the extent of perfusion defects.