Publications by authors named "Ankita Rungta Kapoor"
Article Synopsis
- The 2018 revision of the International Federation of Gynaecology and Obstetrics staging has introduced uncertainties in treatment approaches for node-positive cervical cancer patients, leading to a study aimed at identifying those who will benefit from elective para-aortic lymph node (PALN) irradiation.
- This ongoing multicenter phase III clinical trial involves 274 subjects divided into two groups to compare the effectiveness of limited elective PALN irradiation against no irradiation, with a primary focus on 3-year disease-free survival and various secondary endpoints related to survival and quality of life.
- The study has received ethical approval and is set to be monitored according to guidelines, with the intention to publish findings in reputable scientific journals.
Background: Cervical cancer requires multimodality therapy, resulting in acute toxicities. Intensity-modulated radiation therapy (IMRT) is postulated to spare bone marrow (BM) and bowel to reduce acute hematological and gastrointestinal (GI) toxicities of chemoradiotherapy.
Patients And Methods: This is a prospective randomized phase III study enrolling patients with Stage IB to IVA cervical carcinoma in two arms receiving either three-dimensional conformal radiotherapy (3DCRT) or IMRT from December 2017 to December 2019.
Rhabdomyosarcomas (RMS) are pediatric soft-tissue sarcomas arising from immature mesenchymal cells that are intended to form striated skeletal muscles. Brachytherapy delivers high-dose of precised radiation to the target tissue with high conformity, sparing the nearby normal tissues, hence allowing dose escalation and reducing the likelihood of normal tissue toxicity. There is a scarcity of reports on the use of brachytherapy for extremity RMS.
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