Publications by authors named "Ankita Rawat"

Background: Literature shows that home confinement during coronavirus disease 2019 (COVID-19) pandemic has significantly affected sleep. However, such information regarding subjects having Parkinson's disease (PD) is unavailable.

Methods: This cross-sectional study was conducted using a questionnaire, developed and validated by experts.

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Uropathogenic (UPEC), especially associated with severe urinary tract infections (UTI) pathologies, harbors an important virulence factor known as α-hemolysin (110 kDa). Hemolytic activity of α-hemolysin (HlyA) requires modification (acylation) of two lysine residues of HlyA by HlyC, part of operon . Most of the previous studies had used whole operon and gene cloning for the production of active α-hemolysin.

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In the present study, water quality of 16 springs, located along National Highway-58 from Rishikesh to Badrinath in India, was assessed by determining various physicochemical and microbiological parameters in three different seasons, i.e., pre-monsoon, monsoon, and post-monsoon.

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Article Synopsis
  • Reticulocyte invasion by Plasmodium vivax relies on the Duffy-binding protein (PvDBP) interacting with the host Duffy antigen receptor for chemokines (DARC), and targeting this interaction could help prevent malaria growth.
  • A Phase I trial with 36 healthy male participants assessed the safety and immune response of the PvDBPII vaccine combined with an adjuvant (GLA-SE), revealing no serious adverse effects and good tolerance.
  • Results showed that all doses of the vaccine produced antibodies that effectively inhibited interactions between PvDBP and DARC, with the highest dose demonstrating the strongest and most enduring antibody response, suggesting potential for future malaria prevention efforts.
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