In B-cell malignancies, there is a periodic presence of monoclonal gammopathies. In a notable multitude of cases with chronic lymphocytic leukemia (CLL), a cluster of antigen-inciting B-cells sometimes shows the presence of monoclonal gammopathy and autoimmune hemolysis simultaneously. The detection of monoclonal proteins or light chains in urine and/or serum is significantly increased in cases of CLL and can be identified using highly sensitive laboratory methods, such as serum protein electrophoresis.
View Article and Find Full Text PDFGerm cell tumors usually occur in the gonads. Extragonadal germ cell tumors (EGCTs) are uncommon, and the head and neck region is a rare primary location. In this region, endodermal sinus tumors are relatively uncommon; they are typically recorded alongside teratomas and infrequently by themselves.
View Article and Find Full Text PDFThyrolipoma is a rare disorder marked by substantial adipose tissue growth inside the thyroid gland. Fatty tissue is frequently seen in salivary glands, thymus, breasts, and pancreas but rarely in the thyroid gland. The fascinating and unusual illness known as thyrolipoma presents challenging diagnostic and therapeutic issues.
View Article and Find Full Text PDFOne of the most common oral malignancies is oral squamous cell carcinoma (OSCC). Although the prevalence of oral cancer varies worldwide, it is generally agreed that the oral cavity is a common anatomical site for cancer, depending primarily on the country (and even particular region in some countries) and gender of the patients. Finding diagnostic markers for OSCC is critical for early diagnosis and personalised treatment of patients.
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