Publications by authors named "Ankit Bansal"

Introduction: The left atrium (LA) dilates and its function decreases as a chronic secondary change in hypertrophic cardiomyopathy (HCM). LA strain is a more sensitive measure of LV filling pressure than LA volume and can be used to predict the functional capacity in HCM.

Objective: To analyze LA strain in patients with HCM and its correlation with exercise tolerance.

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Article Synopsis
  • The article provides a formal correction to a previous publication associated with the DOI: 10.1371/journal.pone.0291090.
  • The correction may address errors or inaccuracies found in the original article, ensuring that the information presented is accurate and reliable.
  • This corrected version maintains the integrity of the research and contributes to the overall body of knowledge in its field.
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Objective: To evaluate role of rajyoga meditation (RYM) versus stress management counselling (SMC) in addressing burnout syndrome and resultant improvement in electrocardiogram (ECG) so as to automate burnout prediction from raw ECG data with machine learning (ML).

Methods: Healthcare providers were assigned to two groups: RYM (n = 100) or SMC (n = 102). Subjects in RYM received rajyoga for 3 months including one week offline and thereafter, virtual mode.

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  • The study investigates the characteristics of coronary artery disease in young adults (≤35 years) compared to older adults (>60 years) who experienced ST-segment elevation myocardial infarction (STEMI).
  • Using optical coherence tomography (OCT), researchers found that plaque erosion was more prevalent in younger patients, while plaque rupture was more common in older patients.
  • The study concluded that the mechanisms behind STEMI differ based on age, with young individuals showing more cases of subacute thrombus linked to plaque erosion.
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  • The study focuses on understanding the disparity in cases of peripartum cardiomyopathy (PPCM) among Black patients compared to White patients, particularly in relation to the social vulnerability of their communities.
  • Conducted at a single center from 2000 to 2017, the study found that Black patients with PPCM were more likely to live in socially vulnerable areas, as indicated by a higher Social Vulnerability Index (SVI) score.
  • Results showed that while ejection fractions at diagnosis were similar, Black patients had worse postpartum heart function and lived in communities with higher poverty, unemployment, and single-parent households, highlighting the need for strategies to address these social determinants of health.
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Objectives: The persistence and outcomes following myocardial injury subsequent to coronavirus disease-2019 (COVID-19) infection has not been properly elucidated. We assessed sub-clinical bi-ventricular dysfunction using speckle tracking echocardiography (STE) in post COVID-19 patients.

Methods: A total of 189 subjects following recovery from COVID-19 infection were enrolled.

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  • Culotte stenting is a treatment method for bifurcation lesions of the left main coronary artery that has proven effective but can lead to side branch restenosis due to gaps at the ostium.
  • A study found that performing sequential kissing balloon dilation before main vessel stenting can help prevent these gaps, which is important for successful outcomes.
  • In a report of 45 patients treated with double kissing mini-culotte stenting, there were no major adverse events, and the procedure showed low rates of complications and side branch restenosis at the one-year follow-up.
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  • The study examines the differences in risk factors and outcomes for ST-Segment Elevation Myocardial Infarction (STEMI) patients under 50 years compared to those 50 and older in North India.
  • Among the 5,335 patients studied, young patients attended the hospital earlier, displayed higher rates of physical inactivity and alcohol use, but had lower rates of diabetes and hypertension compared to older patients.
  • Despite a higher prevalence of tobacco use, young STEMI patients experienced lower in-hospital and 30-day mortality rates, primarily due to better heart function upon admission.
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Background: Primary percutaneous intervention (PPCI) of the saphenous vein graft (SVG) is associated with a high risk of distal embolization and no reflow, since SVG lesions are often very friable and have a large thrombotic burden. We report a case of successful PPCI of the SVG using guide catheter thrombectomy with novel double wire technique.

Case Summary: A 60-year-old male with a past history of coronary artery bypass grafting presented with acute thrombotic occlusion of the SVG to the obtuse marginal graft.

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Background: Genetic polymorphism in endothelial Nitric Oxide Synthase (eNOS) are associated with occurrence of multiple cardiovascular diseases (CVDs).

Methods: This study included 300 young ST-segment elevation myocardial infarction (STEMI) patients and 300 healthy controls. STEMI patients were divided into two groups: premature coronary artery disease [CAD] (STEMI<40 years of age) and older STEMI (>40 years of age).

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Background: The short-term clinical outcomes of first-generation thicker-strut durable polymer-based drug-eluting stents (DES) have been widely examined. However, there is a scarcity on qualitative research on the long-term usage of DES that evaluated the thinner strut biodegradable stents for coronary artery disease. Hence, we sought to investigate the long-term safety and performance of thinner strut biodegradable polymer-based BioMime sirolimus-eluting coronary stent system in real-world patients with symptomatic ischemic heart disease.

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Background: COVID-19 vaccines are highly immunogenic but cardiovascular effects of these vaccines have not been properly elucidated.

Objectives: To determine impact of COVID-19 vaccination on mortality following acute myocardial infarction (AMI).

Methods: This was a single center retrospective observation study among patients with AMI enrolled in the the North India ST-Elevation Myocardial Infarction (NORIN-STEMI) registry.

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Article Synopsis
  • Low- and middle-income countries, especially India, face a significant burden from coronary artery disease, yet there is limited data on STEMI patients in these areas.
  • A study of 3,635 STEMI patients in Northern India revealed that a significant portion were young and had common risk factors like smoking and hypertension, with 30-day and 1-year mortality rates at 9% and 11% respectively.
  • Female patients were less likely to receive optimal treatment (PCI) and experienced over twice the mortality rate compared to males, highlighting a critical health disparity that needs to be addressed.
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Background: Psychosocial factors such as stress have been previously implicated as a risk factor for cardiovascular diseases (CVDs). There is little evidence regarding the prevalence of stress among patients with acute myocardial infarction (AMI).

Methods: A total of 903 patients with AMI enrolled in the North Indian ST-Segment Elevation Myocardial Infarction (NORIN-STEMI) registry were included in this study.

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Background: There is an increasing prevalence of coronary artery disease (CAD) in younger individuals. Lipid biomarkers such as lipoprotein-a (Lp-a), Apo A1, Apo B and Paraoxonase-1 (PON1) serve as important risk predictors for development of CAD. There is little evidence regarding the role of lipid biomarkers and their genetic polymorphisms in young (<50 years) ST-segment elevation myocardial infarction (STEMI) patients.

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Background: Genetic polymorphism in MMPs are associated with multiple adverse CV events. There is little evidence regarding role of MMPs and their genetic polymorphisms in young (<50 years) ST-segment elevation myocardial infarction (STEMI) patients.

Methods: This study included 100 young (18-50 years) STEMI patients and 100 healthy controls.

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Objective: Cardiac involvement in recovered COVID-19 patients assessed by cardiac magnetic resonance imaging (MRI).

Methods: Subjects recently recovered from COVID-19 and with an abnormal left ventricular global longitudinal strain were enrolled. Cardiac MRI in all the enrolled subjects was done at baseline (within 30-90 days following recovery from COVID-19) with a follow-up scan at 6 months in individuals with an abnormal baseline scan.

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Resource coordination in surgical scheduling remains challenging in health care delivery systems. This is especially the case in highly-specialized settings such as coordinating Intraoperative Neurophysiologic Monitoring (IONM) resources. Inefficient coordination yields higher costs, limited access to care, and creates constraints to surgical quality and outcomes.

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Unlabelled: Aortic coarctation presenting with neurological complications as compressive myelopathy is rare. We report a case of a 43-year-old, hypertensive, female who presented with gradually progressive paraparesis over 4 years. She was diagnosed to be having coarctation of the aorta with intra-spinal collaterals causing compressive myelopathy.

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Background: Dysglycemia is a major and increasingly prevalent cardiometabolic risk factor worldwide, but is often undiagnosed even in high-risk patients. We evaluated the impact of protocolized screening for dysglycemia on the prevalence of prediabetes and diabetes among patients presenting with ST-segment elevation myocardial infarction (STEMI) in North India.

Methods: We conducted a prospective NORIN STEMI registry-based study of patients presenting with STEMI to two government-funded tertiary care medical centers in New Delhi, India, from January to November 2019.

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  • * Out of 3,597 patients, a significant number presented with reduced LVEF, with nearly 50% having LVEF less than 40%, which correlated with an increased risk of mortality over one year.
  • * Despite high initial discharge rates on guideline-directed therapies, patient adherence to these treatments after one year was notably low, highlighting the need for improved access to timely care and better treatment compliance in these regions.
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Introduction: Juvenile nasopharyngeal angiofibroma(JNA) are highly vascular benign tumours originating in the sphenopalatine fossa and may extend to the pterygopalatine fossa, paranasal sinuses, and nasal cavity. The management of JNA has evolved greatly with development of endoscopy. Treatment modality has changed from open approach to endoscopic approach due to various advantages offered by the endoscopic approach.

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A 38-year-old female was found to have severe mitral stenosis, severe pulmonary arterial hypertension with moderate tricuspid regurgitation, dilated right atrium, persistent left superior vena cava, and hugely dilated coronary sinus. The scheduled balloon mitral valvotomy via trans-femoral approach was abandoned after the venogram revealed the presence of left-sided inferior vena cava with hemi-azygos continuation draining into coronary sinus via left-sided superior vena cava. Balloon mitral valvotomy was attempted from the right trans-jugular route, but we were unable to puncture the inter-atrial septum due to the hugely dilated coronary sinus and right atrium.

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Background: Risk prediction following ST-Elevation Myocardial Infarction (STEMI) in resource limited countries is critical to identify patients at an increased risk of mortality who might benefit from intensive management.

Methods: North India ST-Elevation Myocardial Infarction (NORIN-STEMI) is an ongoing registry that has prospectively enrolled 3,635 STEMI patients. Of these, 3191 patients with first STEMI were included.

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