Publications by authors named "Ankelien-Solveig Duchow"

Article Synopsis
  • A study investigated the effectiveness of intravenous immunoglobulins (IVIGs) for treating acute myelin oligodendrocyte glycoprotein antibody disease (MOGAD) attacks.
  • The research involved analyzing data from 39 patients across seven neuroimmunology centers, focusing on patient demographics and symptoms before and after IVIG treatment.
  • Results showed significant improvements in disability and visual acuity following IVIG administration, suggesting it may be a beneficial treatment for MOGAD, although further studies are needed to confirm these findings.
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Background: Large-scale disease overarching longitudinal data are rare in the field of neuroimmunology. However, such data could aid early disease stratification, understanding disease etiology and ultimately improve treatment decisions. The Berlin Registry of Neuroimmunological Entities (BERLimmun) is a longitudinal prospective observational study, which aims to identify diagnostic, disease activity and prognostic markers and to elucidate the underlying pathobiology of neuroimmunological diseases.

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Background: In neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), neutrophils are found in CNS lesions. We previously demonstrated that NMOSD neutrophils show functional deficiencies. Thus, we hypothesized that neutrophil accumulation in the CNS may be facilitated by impairments affecting mechanisms of neutrophil death.

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