Publications by authors named "Anke Breine"
Article Synopsis
- Phage therapy is a new way to fight germs that are super tough against antibiotics, especially in hospitals.
- Scientists are figuring out how to create special mixes of viruses called phages that can target specific strains of a dangerous germ called Acinetobacter baumannii.
- By studying where these germs are found in the world, researchers can prepare special phage treatments for different regions, which has been shown to work well in tests and with animals.
In this study, we evaluated the antimicrobial activity of bacteria isolated from the marine sponges Hymeniacidon perlevis and Halichondria panicea against seven Acinetobacter baumannii strains, the majority of which were clinically relevant carbapenem-resistant A. baumannii strains. We observed the inhibitory activity of 18 (out of 114) sponge-isolated bacterial strains against all A.
View Article and Find Full Text PDFObjectives: The spread of antibiotic resistant bacteria is an important threat for human health. bacteria impose such a major issue, as multidrug- to pandrug-resistant strains have been isolated, rendering some infections untreatable. In this context, carbapenem-resistant bacteria were ranked as top priority by both WHO and CDC.
View Article and Find Full Text PDFWe identify a new mechanism mediating capsule production and virulence in the WHO and CDC priority ESKAPE pathogen Acinetobacter baumannii. Non-capsulated and avirulent bacteria can revert into a capsulated and virulent state upon scarless excision of an ISAba13 insertion sequence under stress conditions. Reversion events fully restore capsule production and in vivo virulence.
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