Publications by authors named "Ankang Gao"

Dolphin swimming has been a captivating subject, yet the dorsal fin's hydrodynamics remain underexplored. In this study, we conducted three-dimensional simulations of flow around a wall-mounted dolphin dorsal fin derived from a real dolphin scan. The NEK5000 (spectral element method) was employed with a second-order hex20 mesh to ensure high simulation accuracy and efficiency.

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Article Synopsis
  • - The study focused on distinguishing between solid gliomas and brain inflammation using diffusion-weighted imaging (DWI) metrics, which can be challenging in clinical settings.
  • - Researchers analyzed MRI data from 57 patients, assessing various DWI models and metrics like non-Gaussianity, mean kurtosis, and intracellular volume fraction to evaluate their effectiveness in diagnosis.
  • - The results indicated that the MAP model's non-Gaussianity metric had the highest diagnostic performance, followed closely by the DKI model's mean kurtosis, while the DTI model showed the least effectiveness.
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Background: Preoperative differentiation of glioblastoma multiforme (GBM) and solitary brain metastasis (SBM) contributes to guide neurosurgical decision-making.

Purpose: To explore the value of histogram analysis based on neurite orientation dispersion and density imaging (NODDI) in differentiating between GBM and SBM and comparison of the diagnostic performance of two region of interest (ROI) placements.

Study Type: Retrospective.

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Objectives: We aimed to develop and validate radiomic nomograms to allow preoperative differentiation between benign- and malignant parotid gland tumors (BPGT and MPGT, respectively), as well as between pleomorphic adenomas (PAs) and Warthin tumors (WTs).

Materials And Methods: This retrospective study enrolled 183 parotid gland tumors (68 PAs, 62 WTs, and 53 MPGTs) and divided them into training (n = 128) and testing (n = 55) cohorts. In total, 2553 radiomics features were extracted from fat-saturated T2-weighted images, apparent diffusion coefficient maps, and contrast-enhanced T1-weighted images to construct single-, double-, and multi-sequence combined radiomics models, respectively.

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Several functional magnetic resonance imaging (fMRI) studies have demonstrated abnormalities in static intra- and interhemispheric functional connectivity among diverse brain regions in patients with major depressive disorder (MDD). However, the dynamic changes in intra- and interhemispheric functional connectivity patterns in patients with MDD remain unclear. Fifty-eight first-episode, drug-naive patients with MDD and 48 age-, sex-, and education level-matched healthy controls (HCs) underwent resting-state fMRI.

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Purpose: To investigate the association between clinic-radiological features and glioma-associated epilepsy (GAE), we developed and validated a radiomics nomogram for predicting GAE in WHO grade II~IV gliomas.

Methods: This retrospective study consecutively enrolled 380 adult patients with glioma (266 in the training cohort and 114 in the testing cohort). Regions of interest, including the entire tumor and peritumoral edema, were drawn manually.

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Purpose: To assess the value of histogram analysis, using diffusion kurtosis imaging (DKI), in differentiating glioblastoma multiforme (GBM) from single brain metastasis (SBM) and to compare the diagnostic efficiency of different region of interest (ROI) placements.

Method: Sixty-seven patients with histologically confirmed GBM (n = 35) and SBM (n = 32) were recruited. Two ROIs-the contrast-enhanced area and whole-tumor area-were delineated across all slices.

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Objective: This study was conducted in order to investigate the association between radiomics features and frontal glioma-associated epilepsy (GAE) and propose a reliable radiomics-based model to predict frontal GAE.

Methods: This retrospective study consecutively enrolled 166 adult patients with frontal glioma (111 in the training cohort and 55 in the testing cohort). A total 1,130 features were extracted from T2 fluid-attenuated inversion recovery images, including first-order statistics, 3D shape, texture, and wavelet features.

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Background The isocitrate dehydrogenase genotype and codeletion status are key molecular markers included in glioma pathologic diagnosis. Advanced diffusion models provide additional microstructural information. Purpose To compare the diagnostic performance of histogram features of multiple diffusion metrics in predicting glioma and genotyping.

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Purpose: To compare MRI volume measurements, FLAIR image intensity, Diffusion tensor imaging (DTI) and mean apparent propagator (MAP)-MRI measurements in hippocampus ipsilateral and contralateral to the epileptogenic focus for non-invasive lateralization of temporal lobe epilepsy (TLE) and also compare these DTI and MAP-MRI measurements to cognitive function.

Method: A cohort of patients with unilateral TLE and aged-and gendered-matched controls were enrolled in this retrospective study. T1-weighted MPRAGE data for the volume, FLAIR image intensity, DTI and MAP-MRI parameters were performed for bilateral hippocampi of all subjects.

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Background:: Rosai-Dorfman disease (RDD) is typically characterized by painless bilateral and symmetrical cervical lymphadenopathy, with associated fever and leukocytosis. The aim of the current study was to summarize the clinical features and imaging characteristics of RDD, in an effort to improve its diagnostic accuracy.

Methods: The study was analyzed from 32 patients between January 2011 and December 2017; of these, 16 patients had pathologically diagnosed RDD, eight had pathologically diagnosed meningioma, and eight pathologically diagnosed lymphoma.

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Background It is difficult to distinguish between invasive pituitary adenomas (IPAs) and skull base chordomas based on tumor location and clinical manifestations. Purpose To investigate the value of the apparent diffusion coefficient (ADC), T2-weighted (T2W) imaging, and dynamic contrast enhancement (DCE) in differentiating skull base chordomas and IPAs. Material and Methods Data for 21 patients with skull base chordomas and 27 patients with IPAs involving the paranasal sinus were retrospectively reviewed, and all diagnoses were pathologically confirmed.

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