Background: We examined the racial and ethnic distribution of patients with Vogt-Koyanagi-Harada disease (VKH) in a Midwestern US population through a retrospective chart review of patients with VKH seen in a tertiary referral centre between 2012 and 2017. All patients were diagnosed by one uveitis specialist (DAG). We identified 32 patients with VKH seen during this time period.
View Article and Find Full Text PDFOcul Immunol Inflamm
December 2022
Purpose: To determine the utility of routine screening ophthalmic exam in patients with systemic sarcoidosis and no history of uveitis.
Methods: Prospective, single-center, observational study conducted at Northwestern University from October 11, 2012 to October 1, 2020 of new patients with biopsy-proven systemic sarcoidosis and no history of uveitis, referred by medical subspecialists for screening ophthalmic exam.
Results: Forty-nine patients, with mean age of 51 ± 8.
Ocul Immunol Inflamm
November 2021
: To describe clinical manifestations of patients with tubulointerstitial nephritis and uveitis syndrome (TINU) with a focus on posterior segment findings.: Retrospective chart review.: 17 patients were diagnosed with TINU.
View Article and Find Full Text PDFPurpose: To report a case of partial scleral rupture after laser in situ keratomileusis (LASIK) surgery.
Methods: This is a retrospective case report describing a late complication of LASIK surgery.
Results: A 32-year-old white woman with a history of LASIK surgery performed with a mechanical microkeratome 4 years previously presented for evaluation of partial bilateral scleral ruptures.
: To describe tuberculous uveitis (TU) presenting as a bullous retinal detachment (RD) and to perform a comprehensive literature review on TU with similar features. : Observational case report and systematic literature review. : An 84-year-old woman presented with bilateral granulomatous uveitis and bullous RD in the left eye.
View Article and Find Full Text PDFPurpose Of Review: The aim of this study was to summarize the demographics and causes of paediatric uveitis and to discuss the latest treatment options for noninfectious paediatric uveitis.
Recent Findings: In the last few years, reports out of Europe, Asia and the Americas have shown that the causes of paediatric uveitis can vary greatly geographically. With ongoing research into therapeutics, particularly the development of biologic agents, the treatment of noninfectious entities has evolved over time.
Purpose: Adaptive optics scanning laser ophthalmoscopy (AOSLO) allows en face visualization of specific layers of the retina. This pilot study evaluated the ability of AOSLO to visualize photoreceptor integrity in patients with birdshot chorioretinopathy (BCR).
Method: A total of 16 consecutive patients with HLA-A29+ BCR were imaged using the prototype Apaeros retinal imaging system.
Posterior scleritis in children is very rare. In contrast to the adult form, pediatric posterior scleritis has not previously been associated with any systemic disorder. We describe a case of an 11-year-old girl who presented with left eye pain and redness and was found to have posterior scleritis on ultrasonography.
View Article and Find Full Text PDFBackground: The aim of this study was to report an unusual case of chronic postoperative endophthalmitis following cataract surgery, secondary to Ochrobactrum anthropi that was found to be resistant to vancomycin.
Findings: Anterior chamber paracentesis cultures grew gram negative bacilli Ochrobactrum anthropi. The patient was treated with a series of intracameral injections of moxifloxacin, with adjuvant oral moxifloxacin.
Graefes Arch Clin Exp Ophthalmol
August 2009
Background: To compare spectral domain optical coherence tomography (SDOCT) cross-sectional images of human central retina obtained from donor eyes with and without age-related macular degeneration (AMD) to corresponding histopathology from light micrographs. To establish the utility of SDOCT for localizing pathology in the posterior eyecup, for identifying ocular disease in donor eyes, or for directing subsequent sectioning of retinal lesions for research.
Methods: Seven consecutive human donor eyes were selected based on age.
Purpose: Detect changes in the neurosensory retina using spectral-domain optical coherence tomography (SD OCT) imaging over drusen in age-related macular degeneration (AMD). Quantitative imaging biomarkers may aid in defining risk of disease progression.
Design: Cross-sectional, case-control study evaluating SD OCT testing in AMD.
Objectives: To evaluate the spectrum of foveal architecture in pediatric albinism and to assess the utility of spectral-domain optical coherence tomography (OCT) in ocular imaging of children with nystagmus.
Methods: Spectral-domain OCT imaging was performed on study subjects in 3 groups: subjects with ocular albinism (OA) or suspected OA with foveal hypoplasia, with nystagmus, and with or without iris transillumination; a subject with oculocutaneous albinism and Hermansky-Pudlak syndrome; and control subjects. Dense volumetric scans of each fovea were captured using standard and handheld spectral-domain OCT devices.
Purpose: To categorize drusen ultrastructure in age-related macular degeneration (AMD) using spectral domain optical coherence tomography (SDOCT) and correlate the tomographic and photographic drusen appearances.
Design: Prospective case series.
Participants: Thirty-one eyes of 31 patients with non-neovascular AMD.