Evaluation of suitability and biodegradability of the organophosphate insecticides to mitigate insecticide pollution in onion farming.

Organophosphates constitute a major class of pesticides widely employed in agriculture to manage insect pests. Their toxicity is attributed to their ability to inhibit the functioning of acetylcholinesterase (AChE), an essential enzyme for normal nerve transmission. Organophosphates, especially chlorpyrifos, have been a key component of the integrated pest management (IPM) in onions, effectively controlling onion maggot , a severe pest of onions.

Genome-wide microsatellites and species specific markers in genus revealed through whole genome analysis.

Genome wide microsatellite maps shall support systematics through the development of reliable markers, enabling species discrimination and variability analyses. Whole genome sequences of 17 accessions belonging to 14 species were retrieved from GenBank and the genome-wide microsatellites in each species were mined. A total of 51,200 microsatellites, including dinucleotide to decanucleotide motifs, have been identified across all the species and each one was characterized for uniqueness and repeat number.

Functionalization-Induced Self-Assembly of Polystyrene/Kaolinite in Situ Nanocomposites into Giant Vesicles.

We report a facile functionalization strategy for fabrication of giant, inorganic-polymer hybrid vesicles by controlled aminosilyl/vinylsilyl functionalization (AS/VS) of the aluminol layer in kaolinite (Kaol) by intercalation and subsequent polymerization of styrene with the in situ polystyrene clay nanocomposite (PCN), followed by self-assembly in solvents. The synergistic effect of the AS/VS ratio on functionalization-assisted intercalation of Kaol was established in 1:3AS/VS-Kaol by the greater extent of formation of higher interlayer spacing corresponding to 1.12 nm compared to 1:1AS/VS-Kaol.

Assessment of Symptoms and Quality of Life among Postmenopausal Women in a Tertiary Care Hospital in Kochi, South India: A Hospital-based Descriptive Study.

Background: Menopause is a physiological event in the women's life that can strongly affect the quality of life (QOL). More than 80% of women state that physical and physiological symptoms commonly accompany menopause and affect women's health and well-being.

Objective: The aim of the study was to assess the menopause-related symptoms and their impact on the women's life.

Self-assembly of oleylamine modified nano-fibrillated cellulose from areca husk fibers into giant vesicles.

Nanotechnology involving cellulosic substrates has generated a great attention owing to their exceptional physical and chemical properties. Self-assembled nanostructures obtained from carbohydrate polymers are of interest in the biomedical field for the biocompatibility and non-toxic nature. In the present study modification of nano-fibrillated cellulose (NFC) synthesised from the husk fibers of Areca catechu nuts (AHF) was studied by controlled regio-selective amidation with oleylamine (OA) and characterized.

Patient Reported Outcome Assessment of Periodontal Therapy: A Systematic Review.

Introduction: Patient Reported Outcomes (PROs) are now regarded as a fundamental measure of therapeutic success. Patient's opinion regarding the impact of disease and its treatment is assessed using scales such as Oral Health Related Quality Of Life (OHRQoL) tools. Patient centred outcome assessment is now being considered as a primary outcome measure in clinical trials.

Gamma amino butyric acid accumulation in medicinal plants without stress.

Introduction: Gamma amino butyric acid (GABA) is an important ubiquitous four carbon nonprotein amino acid with an amino group attached to gamma carbon instead of beta carbon. It exists in different organisms including bacteria, plants, and animals and plays a crucial role in humans by regulating neuronal excitability throughout the nervous system. It is directly responsible for the regulation of muscle tone and also effective in lowering stress, blood pressure, and hypertension.

RAPD, SCAR and conserved 18S rDNA markers for a red-listed and endemic medicinal plant species, Knema andamanica (Myristicaceae).

Knema andamanica is a red-listed endemic medicinal species of Myristicaceae restricted to Andaman and Nicobar (A&N) Islands, India. This species is used in tribal medicines and has immense bioprospective potential. With a view to generate suitable genomic markers for classification and identification, we have generated RAPD, SCAR and conserved 18S rDNA markers from K.

Study on drug related hospital admissions in a tertiary care hospital in South India.

Background And Objectives: Accidental and intentional poisonings or drug overdoses constitute a significant source of aggregate morbidity, mortality, and health care expenditure. Studies evaluating drug related hospitalization have estimated that approximately 5-10% of all hospital admissions are drug related. The present study was carried out to investigate type, nature and incidence of drug related admissions in our hospital settings.

Chitosan and enteric polymer based once daily sustained release tablets of aceclofenac: in vitro and in vivo studies.

The purpose of this study was to develop a once daily sustained release tablet of aceclofenac using chitosan and an enteric coating polymer (hydroxypropyl methylcellulose phthalate or cellulose acetate phthalate). Overall sustained release for 24 h was achieved by preparing a double-layer tablet in which the immediate release layer was formulated for a prompt release of the drug and the sustained release layer was designed to achieve a prolonged release of drug. The preformulation studies like IR spectroscopic and differential scanning calorimetry showed the absence of drug-excipient interactions.

Enhancement of dissolution rate and bioavailability of aceclofenac: a chitosan-based solvent change approach.

In this study the significant effect of chitosan on improving the dissolution rate and bioavailability of aceclofenac has been demonstrated by simple solvent change method. Chitosan was precipitated on aceclofenac crystals using sodium citrate as the salting out agent. The pure drug and the prepared co-crystals with different concentrations of chitosan (0.

Preparation, in vitro, preclinical and clinical evaluations of once daily sustained release tablets of aceclofenac.

The objective of the present study was to develop "once daily" sustained release tablets of aceclofenac by direct compression using hydroxypropyl methylcellulose-K4M (HPMC). The solubility studies of aceclofenac were conducted to select suitable dissolution media. The drug-excipient mixtures were subjected to preformulation studies.