Publications by authors named "Anju Nabi"
Article Synopsis
- * Whole-genome sequencing (WGS) of eight isolates revealed the presence of multiple resistance genes, with one isolate showing dual carbapenemase genes and others having colistin resistance.
- * The research underscores the importance of surveillance and antibiotic stewardship to control the spread of these resistant pathogens and emphasizes the significance of accurately identifying resistance mechanisms for effective treatment strategies.
Reports from Arabian Gulf countries have demonstrated emergence of novel methicillin resistant Staphylococcus aureus (MRSA) strains. To address the lack of data from the United Arab Emirates (UAE), genetic characterisation of MRSA identified between December 2017 and August 2019 was conducted using DNA microarray-based assays. The 625 MRSA isolates studied were grouped into 23 clonal complexes (CCs) and assigned to 103 strains.
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- Fusidic acid is a steroid antibiotic used topically for skin infections caused by Staphylococcus aureus, particularly in the face of increasing methicillin-resistant strains (MRSA) that possess specific resistance genes.
- The study explored MRSA isolates from the Arabian Gulf, revealing previously unreported variants of SCCmec elements with the fusC resistance gene, suggesting complex genetic relationships among strains from different countries.
- The findings indicate that MRSA strains with these resistance genes may have a competitive advantage in healthcare and community environments, highlighting the need to reconsider the use of topical antibiotics and restrict their sale without prescriptions.
Objectives: Carbapenem resistance in Pseudomonas aeruginosa is growing and results from variable mechanisms. The objectives of the current study were to investigate mechanisms of carbapenem resistance and genetic relatedness of P. aeruginosa isolates recovered in Dubai hospitals.
View Article and Find Full Text PDFFew studies have addressed the molecular epidemiology of carbapenem-resistant Enterobacteriaceae (CRE) isolates in the Arabian Peninsula, and such investigations have been missing from Dubai, a major economical, tourism and medical centre of the region. The antibiotic susceptibility, the carbapenemase type produced, and the clonality of 89 CRE strains isolated in five major Dubai hospitals in June 2015 to June 2016 were determined. Thirty-three percent of the collection of 70 Klebsiella pneumoniae, 13 Escherichia coli and 6 other Enterobacteriaceae were extremely drug resistant, 27% were resistant to colistin, and 4.
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