Establishment of Real-Time PCR Method to Differentiate (Diptera, Psychodidae) from s.s. Based on Whole Mitochondrial Genome Analysis.

, considered a potential vector for visceral leishmaniasis (VL), is distributed in the southern Gansu and northern Sichuan regions in China. However, the high similarity in the morphology of and s.s.

Enhanced Catalytic Performance of N-Doped Carbon Sphere-Supported Pd Nanoparticles by Secondary Nitrogen Source Regulation for Formic Acid Dehydrogenation.

The development of catalysts with high selectivity, good catalytic activity, and excellent cycle performance is of significance for the application of formic acid (HCOOH, FA) as a hydrogen support. Herein, Pd is deposited on a series of N-doped carbons, which are prepared by cocarbonization of N-containing zeolite imidazole frameworks (ZIF-8) and other N/C sources (melamine, xylitol, urea, and glucose), for hydrogen generation from FA. The results demonstrate that the introduction of a secondary N/C source further affects the catalytic performance of Pd by adjusting the morphology, specific surface area, N content, and type of carbon.

Polyethyleneimine-Modified Amorphous Silica for the Selective Adsorption of CO/N at High Temperatures.

Mechanochemistry is very attractive as an efficient, solvent-free, and simplified technique for the preparation of composite adsorbents. Here, a series of polyethyleneimine (PEI)-modified SiO adsorbents were prepared via mechanical ball milling for selective adsorption of CO at high temperatures. The structural properties of these adsorbents were characterized by XRD, SEM, TGA, FTIR, and N adsorption-desorption.

Highly Efficient Absorption of CO by Protic Ionic Liquids-Amine Blends at High Temperatures.

In view of the increasingly serious harm of CO to the environment, it is highly desirable to develop effective CO absorbents. In this work, we demonstrated an efficient absorption of CO by blends of protic ionic liquids (PILs) plus amines. The density and viscosity of investigative four PILs-amine mixtures were measured.

Real World Outcomes and Hepatotoxicity of Infliximab in the Treatment of Steroid-Refractory Immune-Related Adverse Events.

Background And Aims: Current guidelines state that infliximab is contraindicated for the treatment of immune checkpoint inhibitor-related hepatitis (ir-hepatitis) due to the risk of inducing further liver damage. As this recommendation is largely based on the use of infliximab for rheumatologic diseases, we evaluated the efficacy and hepatotoxicity of infliximab in patients with steroid-refractory immune-related adverse events (irAEs).

Methods: We retrospectively reviewed consecutive patients treated with infliximab for irAEs at Princess Margaret Cancer Centre.

Safety of two-hour intermittent intravenous infusions of tacrolimus in the allogeneic hematopoietic stem cell transplantation unit.

At our institution, tacrolimus is used as a second-line agent for the prevention and treatment of graft-versus-host-disease in the allogeneic hematopoietic stem cell transplantation (HSCT) unit after patients have experienced a serious or intolerable adverse event to cyclosporine. As per our standard practice, tacrolimus is administered via 2-h intermittent IV infusions (IIVs) every 12 h rather than continuous IV infusion. Shorter infusion times are cautioned due to concerns of higher rates of nephrotoxicity, neurotoxicity and infusion-related reactions, although there is a paucity of data to support this claim.

Persistent Diarrhea after Celiac Plexus Block in a Pancreatic Cancer Patient: Case Report and Literature Review.

Background: Neurolytic celiac plexus block is increasingly used to treat refractory pain associated with abdominal malignancies, especially pancreatic cancer. While self-limiting diarrhea can occur commonly in patients post procedure, a very rare risk of persistent diarrhea exists.

Objective: We present a case of a 70 year old female with locally advanced pancreatic adenocarcinoma who was hospitalized for persistent severe diarrhea post celiac plexus block and discuss management options for this adverse effect.

Outpatient parenteral antimicrobial therapy for surgery patients: A comparison with previous standard of care.

Background: Current literature reports that outpatient parenteral antimicrobial therapy (OPAT) programs improve cure rates, and reduce length of hospitalization and costs. OPAT programs are still relatively new in Canada.

Objective: To evaluate the benefits of an OPAT program initiated at a multispecialty tertiary care facility in Toronto, Ontario, compared with the previous standard of care.