Publications by authors named "Anjali Rajhans"
Article Synopsis
- - RNA splicing is essential for generating diversity in RNA and proteins, and the spliceosome complex is crucial for regulating this process; however, abnormal splicing is linked to various diseases, notably different types of cancer.
- - In hepatocellular carcinoma (HCC), which accounts for around 75% of liver cancer cases, many different alternative RNA splicing events have been identified, impacting tumor behavior and patient survival rates.
- - The splicing of genes like MCL1, Bcl-X, and BCL2 can produce variants that either promote or prevent cell death, complicating cancer treatment as some variants resist chemotherapy while others enhance its effectiveness; ongoing research explores therapeutic strategies targeting these splicing events.
