Polyphenol Phase-II Metabolites are Detectable in Human Plasma after Ingestion of C Labeled Spinach-a Pilot Intervention Trial in Young Healthy Adults.

Scope: After intrinsic labeling of spinach (Spinacia oleracea L., Chenopodiaceae) with CO , we investigated if labeled polyphenol metabolites were detectable in human plasma.

Methods And Result: In a pilot intervention trial, five healthy men consumed 5 g freeze-dried C labeled spinach, including a total amount of 160 μmol methoxyflavonols, including 70 μmol 5,3',4'-trihydroxy-3-methoxy-6,7-methylendioxyflavone-4'-glucuronide.