Customized humanoptics silicone iris prosthesis in eyes with posttraumatic iris loss: outcomes and complications.

Purpose: Posttraumatic partial or total iris defects often cause significant debilitating glare, photophobia, decreased vision and cosmetic problems. Currently, the best cosmetic results can be obtained with a customized silicone iris prosthesis. However, little is known about the functional results and the rate of complication if this type of iris prosthesis is implanted into severely traumatized eyes.

InFlow microscopy of human leukocytes: A tool for quantitative analysis of actin rearrangements in the immune synapse.

The actin cytoskeleton is a main component to preserve the cell shape. It represents a cellular machinery that enables morphological changes and orchestrates important dynamic cellular functions. Thereby, it supports T-cell migration, immune synapse formation, activation and execution of effector functions.