Publications by authors named "Anja Gaeckler"
Front Microbiol
June 2023
Article Synopsis
- The study investigates the adaptive immune response in patients with post-acute sequelae of COVID-19 (PASC), focusing on the role of SARS-CoV-2 specific immunity.
- It compares immune responses, particularly CD4+ and CD8+ T cell responses, between PASC patients and healthy COVID-19 convalescents, finding that PASC patients exhibit a stronger but low avidity CD8+ T cell response.
- The findings suggest that an inflammatory response from activated low avidity pro-inflammatory CD8+ T cells may contribute to tissue damage and symptoms seen in PASC patients, indicating the need for more research to clarify the underlying mechanisms.
