Cassia auriculata and its role in infection / inflammation: A close look on future drug discovery.

The herbal plants contain various active compounds which have the ability to treat several human diseases without any side effects like cancer chemotherapeutic drugs used currently. It is reported that majority of the presently used drugs are derived from natural resources like plants or their products and hence, there is an urgent need to search for novel drugs from natural resources. Accordingly, the present study was designed to exploit an ethnomedicinally important plant Cassia auriculata Linn.

Chronic Inflammatory-Modulating Potential of with Proinflammatory Cytokine IL-1beta and Its Anticancer Effect on Lung Cancer Cell Line.

Background: Inflammation is a key element in tumor progression, over time, persistent inflammation causes damage to DNA and leads to cancer. The relationship between chronic inflammation and tumor development is well established, blocking of which can help in cancer prevention and treatment in the future.

Objective: Hence, with this background, the present study aims to evaluate the anti-inflammatory and anticancer potential of Cassia auriculata (CA) solvent fractions through in silico and in vitro means, respectively.

and approaches to evaluate the bioactivity of Cassia auriculata L extracts.

The present study is an attempt to evaluate the anti-inflammatory and anticancer potentials of the plant (CA). The aerial parts of CA were subjected to solvent extraction, and the extracts were fractionised by gas chromatography and mass spectrometry analysis for its phytochemical content. The antiinflammatory activity of the extracts were confirmed by the IC value of 125.