Publications by authors named "Anita van Loenhoud"
Article Synopsis
- The study explores how cerebrospinal fluid (CSF) biomarkers relate to brain atrophy and cognitive decline in Alzheimer's disease, aiming to understand why tau pathology doesn't always correlate with these issues.
- Researchers analyzed data from 428 amyloid-positive participants, using various tests and brain imaging to assess the impact of 18 CSF proteins on brain health and cognitive performance over time.
- Results showed that in Alzheimer's dementia, certain vascular integrity biomarkers decreased the negative effects of tau pathology on brain atrophy, while in mild cognitive impairment, increased NfL levels were linked to greater cortical atrophy and reduced cortical thickness.
Parkinson's disease (PD) is often associated with cognitive deficits, although their severity varies considerably between patients. Recently, we used voxel-based morphometry (VBM) to show that individual differences in gray matter (GM) volume relate to cognitive heterogeneity in PD. VBM does, however, not differentiate between cortical thickness (CTh) and surface area (SA), which might be independently affected in PD.
View Article and Find Full Text PDFThis study investigated whether working memory training is effective in enhancing verbal memory in children with low language abilities (LLA). Cogmed Working Memory Training was completed by a community sample of children aged 8-11 years with LLA and a comparison group with matched non-verbal abilities and age-typical language performance. Short-term memory (STM), working memory, language, and IQ were assessed before and after training.
View Article and Find Full Text PDF