Non-speculum clinician-taken samples for human papillomavirus testing: a cross-sectional study in older women.

Background: Cervical cancer incidence and mortality are high in women aged ≥65 years, despite the disease being preventable by screening. Speculum-based screening can become more uncomfortable after the menopause.

Aim: To examine test performance and acceptability of human papillomavirus (HPV) testing on clinician-collected vaginal samples without a speculum (non-speculum).

Non-speculum sampling approaches for cervical screening in older women: randomised controlled trial.

Background: Cervical cancer disproportionately affects women ≥65 years, especially those not screened regularly. Speculum use is a key barrier.

Aim: To assess if offering non-speculum clinician-taken sampling and self-sampling increases uptake for lapsed attenders aged 50-64 years.

Lectins in Cervical Screening.

Cervical screening in low-resource settings remains an unmet need. Lectins are naturally occurring sugar-binding glycoproteins whose binding patterns change as cancer develops. Lectins discriminate between dysplasia and normal tissue in several precancerous conditions.

Acceptability of non-speculum clinician sampling for cervical screening in older women: A qualitative study.

Objectives: One reason that women over age 50 report avoiding cervical screening is increased discomfort postmenopause. This study aimed to explore the acceptability of human papillomavirus testing on clinician-collected vaginal samples without a speculum ('non-speculum') for cervical screening among older women.

Methods: Thirty-eight women in England aged 50-64 with a range of cervical screening experience ('up-to-date' n = 17, 'overdue screening' n = 18, 'never screened' n = 3) were identified via a recruitment agency.

Cytology in the diagnosis of cervical cancer in symptomatic young women: a retrospective review.

Background: Cervical cancer in young women presents a diagnostic challenge because gynaecological symptoms are common but underlying disease is rare.

Aim: To explore the potential for using cytology as a diagnostic aid for cervical cancer in young women.

Design And Setting: Retrospective review of primary care records and cytology data from the national cervical screening database and national audit of cervical cancers.

Offering self-sampling to cervical screening non-attenders in primary care.

Objectives To assess the feasibility and acceptability of offering self-sampling for Human Papillomavirus (HPV) testing to cervical screening non-attenders when they consult primary care for any reason. Methods In a pilot implementation study, six general practices in London, UK, offered self-sampling kits during consultation to women aged 25-64 who were at least six months overdue for cervical screening (no cytology test recorded in the past 3.5 years if aged 25-49, or 5.