Publications by authors named "Anita Ebrahimpour"
Article Synopsis
- Non-specific chronic low back pain (CLBP) is a widespread issue that persists despite various treatments, and this study investigates the effectiveness of repetitive transcranial magnetic stimulation (rTMS) on alleviating pain in these patients.
- The research involved 15 CLBP patients who underwent rTMS, measuring pain intensity and brain activity through fMRI before and after treatment, with findings indicating a significant reduction in pain intensity (36.22%).
- Results showed a positive correlation between brain activity in the insula and pain levels, while activity in the medial prefrontal cortex negatively correlated, suggesting that changes in specific brain regions may be linked to pain reduction in CLBP when subjected to rTMS.
Purpose: Gadolinium-enhancing necrosis in glioblastoma multiforme (GBM), as an occasionally occurring false positive in contrast enhancement (CE) imaging, leads to trouble for segmentation of GBM and treatment. Therefore, the investigation of complementary detection way to identify the metabolically active volume of the tumor with high reliability is very worth to be addressed. Here, we reported on a case of GBM with gadolinium-enhancing necrosis in an experimental CE imaging study in mice and evaluated the discrimination of the necrosis and metabolically active parts of the GBM using conventional and state-of-the-art susceptibility-based MRI.
View Article and Find Full Text PDFThe preparation of multifunctional smart theranostic systems is commonly achieved through complicated strategies, limiting their biomedical applications. (SP) microalgae, as a natural helix with some of the intrinsic theranostic functionalities (e.g.
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- Dopamine is a key neurotransmitter linked to various neurological and mental health issues, where its release and function can be disrupted.
- The study utilized dendrimer-conjugated dopamine to track its distribution in the body using SPECT imaging while ensuring the compound was non-toxic to human kidney cells.
- Results indicated that dopamine D1 receptors concentrated significantly in the liver, maintaining specificity for the targeted organ.
Article Synopsis
- A novel method for detecting glioblastoma multiforme (GBM) was developed using the combination of 5-aminolevulinic acid (ALA) and iron supplements, specifically ferric ammonium citrate (FAC), evaluated through R' and quantitative susceptibility mapping (QSM).
- In experiments with glioblastoma cells and Wistar rats, results showed significantly higher intracellular iron accumulation after sequential treatment with ALA and FAC compared to control groups.
- The study demonstrated that this treatment not only enhanced iron deposition in glioma cells but also improved the detection capabilities of 3 T MRI for identifying GBM through increased relaxivity and magnetic susceptibility values.
Background: In diffuse optical tomography, determining the optimal angle between the source and detector is an effective method to reduce the number of projections while maintaining the quality of the reconstructed images. In this study, a new parameter is introduced to evaluate the source-detector geometries.
Methods: A two-dimensional mesh with the radius of 20 mm and 7987 nodes were built.
Background: Molecular fluorescence imaging is widely used as a noninvasive method to study the cellular and molecular mechanisms. In the optical imaging system, the sensitivity is the change of the intensity received by the detector for the changed optical characteristics (fluorescence) in each sample point. Sensitivity could be considered as a function of imaging geometry.
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