Plant growth-promoting bacteria Kosakonia radicincitans mediate anti-herbivore defense in Arabidopsis thaliana.

This study demonstrates that the application of the PGPB strain, Kosakonia radicincitans enhances a plant's resistance against phloem-feeding and chewing insects in Arabidopsis thaliana. The plant growth-promoting bacterial strain K. radicincitans DSM 16656 applied to A.

Community-based control of the brown dog tick in a region with high rates of Rocky Mountain spotted fever, 2012-2013.

Rocky Mountain spotted fever (RMSF) transmitted by the brown dog tick (Rhipicephalus sanguineus sensu lato) has emerged as a significant public health risk on American Indian reservations in eastern Arizona. During 2003-2012, more than 250 RMSF cases and 19 deaths were documented among Arizona's American Indian population. The high case fatality rate makes community-level interventions aimed at rapid and sustained reduction of ticks urgent.

Impact of the PGPB Enterobacter radicincitans DSM 16656 on growth, glucosinolate profile, and immune responses of Arabidopsis thaliana.

Plant growth-promoting bacteria (PGPB) affect plant cellular processes in various ways. The endophytic bacterial strain Enterobacter radicincitans DSM 16656 has been shown to improve plant growth and yield in various agricultural and vegetable crops. Besides its ability to fix atmospheric nitrogen, produce phytohormones, and solubilize phosphate compounds, the strain is highly competitive against native endophytic organisms and colonizes the endorhizosphere in high numbers.

The Arabidopsis mitogen-activated protein kinase phosphatase PP2C5 affects seed germination, stomatal aperture, and abscisic acid-inducible gene expression.

Abscisic acid (ABA) is an important phytohormone regulating various cellular processes in plants, including stomatal opening and seed germination. Although protein phosphorylation via mitogen-activated protein kinases (MAPKs) has been suggested to be important in ABA signaling, the corresponding phosphatases are largely unknown. Here, we show that a member of the Protein Phosphatase 2C (PP2C) family in Arabidopsis (Arabidopsis thaliana), PP2C5, is acting as a MAPK phosphatase.

Effect of withdrawal of co-proxamol on prescribing and deaths from drug poisoning in England and Wales: time series analysis.

Objective: To assess the effect of the UK Committee on Safety of Medicines' announcement in January 2005 of withdrawal of co-proxamol on analgesic prescribing and poisoning mortality.

Design: Interrupted time series analysis for 1998-2007.

Setting: England and Wales.

Alcohol-related and hepatocellular cancer deaths by country of birth in England and Wales: analysis of mortality and census data.

Background: The incidence of and mortality from alcohol-related conditions, liver disease and hepatocellular cancer (HCC) are increasing in the UK. We compared mortality rates by country of birth to explore potential inequalities and inform clinical and preventive care.

Design: Analysis of mortality for people aged 20 years and over using the 2001 Census data and death data from 1999 and 2001-2003.

Geographical variations in deaths related to drug misuse in England and Wales, 1993-2006.

Drug misuse is a significant public health issue in England and Wales. This article examines geographical variations in drug misuse mortality in England and Wales over the period 1993 t 2006. Geographical variations in deaths related to drug misuse have generally persisted over this period, one of substantial change in these deaths (with a peak in 2001 and numbers in 2006 being almost double those in 1993), although there were some significant changes to the regional level pattern.

Identification of genes involved in siderophore transport in Streptomyces coelicolor A3(2).

The potential iron siderophore transporter genes have been determined from the genome sequence of Streptomyces coelicolor A3(2). One of these gene clusters, cdtABC, was disrupted and characterized to determine its role in the uptake of the siderophores produced by S. coelicolor.

The impact of introducing ICD-10 on analysis of respiratory mortality trends in England and Wales.

This article examines the impact of the introduction of ICD-10 on respiratory disease mortality statistics in England and Wales, specifically focussing on pneumonia, chronic lower respiratory diseases, and influenza. The main changes are highlighted and the article explains how figures can be adjusted to take account of these changes so that trends over time can be analysed. The number of deaths assigned to the respiratory disease chapter of the ICD as a whole decreased by 22 per cent as a result of the introduction of ICD-10.

Leading causes of death in England and Wales--how should we group causes?

This article examines how best to identify the leading causes of mortality in England an Wales, by using different way of grouping causes of death, based on a list developed by the World Health Organization (WHO). Four different versions of this list are compared. The leading cause of death across all age groups depends on the ways in which common diseases and external causes are aggregated or disaggregated into groups.

The impact of introducing ICD-10 on trends in mortality from circulatory diseases in England and Wales.

This article examines the impact of the introduction of ICD-10 on mortality from circulatory diseases in England and Wales. The article examines changes to specific types of circulatory disease, focussing on ischaemic heart disease (IHD) and cerebrovascular disease (stroke). The main changes are highlighted and the article explains how data can be adjusted to take account of these changes so that trends over time can be analysed.

The effect of the introduction of ICD-10 on cancer mortality trends in England and Wales.

This article examines changes in deaths assigned to malignant and non-malignant neoplasms resulting from the introduction of ICD-10 in England and Wales. In particular the Government's target of reducing mortality rates from malignant cancers on those aged under 75. The main changes are highlighted and the article explains how data can be adjusted to take account of these changes so that trends in mortality rates over time can be analysed.

Trends in mortality and hospital admissions associated with epilepsy in England and Wales during the 1990s.

This article examines trends in mortality and hospital admissions associated with epilepsy in England and Wales during the 1990s. Mortality data were analysed for the period 1993 to 2000. Data on hospital admissions where the main diagnosis was epilepsy were obtained from the Hospital Episode Statistics information service of the Department of Health and analysed for the period 1991/92 to 2000/01.