Publications by authors named "Anishah Mandani"
Article Synopsis
- Researchers developed a mouse model (ApoE/ArKO) lacking apolipoprotein E and aromatase to study breast cancer in the context of metabolic syndrome, as these patients often have worse outcomes.
- In experiments, ApoE/ArKO mice with implanted breast cancer cells showed significantly more tumor growth compared to wild-type mice, with notable differences in factors like insulin-like growth factor binding protein-5, though metastasis rates were lower in these mice.
- This new mouse model is valuable for exploring how metabolic syndrome influences breast cancer biology and may lead to a better understanding of treatment outcomes.
