Efficacy of Simvastatin in Bone Regeneration After Surgical Removal of Mandibular Third Molars: A Clinical Pilot Study.

Introduction: Simvastatin, a common cholesterol-lowering drug that inhibits hepatic hydroxymethylglutaryl coenzyme A reductase, the rate-limiting enzyme in the mevalonate pathway, increases expression of the BMP-2 gene and thus promotes bone regeneration.

Materials And Methods: A study was conducted in mandibular third molar sockets to study the efficacy of the drug by implanting it into sockets (experimental group) and observations were made over 3 months to compare the healing with the (control group).

Conclusion: The results showed faster regeneration of the bone in the simvastatin site using the gray level histogram values.

Juvenile ossifying fibroma of mandible: a case report.

Fibro osseous lesions are benign mesenchymal skeletal tumours in which mineralized tissue, blood vessels and giant cells, in varied proportions replace normal bone. Included in this group are fibrous dysplasia (FD), cherubism, ossifying fibroma and osteoblastoma. Although fibro osseous lesions have similar histologic and radiographic features, they may exhibit a wide range of biological behaviours.

Efficacy of platelet rich plasma and hydroxyapatite crystals in bone regeneration after surgical removal of mandibular third molars.

Purpose: This study evaluates the efficacy of platelet rich plasma (PRP) & porous hydroxyapatite crystals in bone regeneration after surgical removal of mandibular third molar with the help of radiographs and its comparison with control side.

Materials And Methods: A total of 40 patients; both male and female aged between 18 and 35 years, who had impacted mandibular third molars were randomly selected for this study. Twenty patients were taken for control group and 20 patients for study group.

Comparison of primary and secondary closure of the surgical wound after removal of impacted mandibular third molars.

Aims And Objectives: This comparative study compares the primary and secondary healing after surgical removal of impacted mandibular third molars, evaluating and monitoring the extent of swelling and severity of pain and trismus.

Materials And Methods: 60 patients (37 females, 23 males; age range 18-40 years) were included in the series. The patients were randomly subdivided into 2 groups of 30 each.

Effectiveness of human amnion as a graft material in lower anterior ridge vestibuloplasty: a clinical study.

Objective: The aim of this study is to evaluate the clinical use of amnion as a biodegradable graft material for lower anterior ridge vestibuloplasty.

Study Design: Ten patients who had been referred for preprosthetic surgery underwent mandibular anterior ridge vestibuloplasty using Clark's technique and amniotic membrane as a graft material. Preoperative vestibular depth was measured.

Healing of intraoral wounds closed using silk sutures and isoamyl 2-cyanoacrylate glue: a comparative clinical and histologic study.

Purpose: To compare the clinical and histologic healing of intraoral wounds closed using No. 3-0 silk suture with that obtained with isoamyl 2-cyanoacrylate glue.

Materials And Methods: We performed alveoloplasty in 30 cases in the mandibular anterior region of edentulous arches; the length of incision in all cases was the same distance from the midline.

Randomized double blind comparative study on the efficacy of Ibuprofen and aceclofenac in controlling post-operative sequelae after third molar surgery.

Objective: To compare the efficacy of Ibuprofen and Aceclofenac in controlling pain, swelling and trismus following removal of impacted mandibular third molar teeth. To assess the patient's acceptability of these drugs.

Methods: The present double blind study was conducted on 60 adult patients for the surgical removal of impacted mandibular third molars.

Squamous cell carcinoma in a maxillary odontogenic keratocyst: A rare entity.

Odontogenic cysts in the maxilla are common but a malignant change in an odontogenic cyst is a comparatively a rare occurrence; however, these entities present with clinical and radiographic features similar to benign, expansible, central, odontogenic tumor, or cyst of the jaws. A patient reporting with squamous cell carcinoma arising from an odontogenic keratocyst of right maxilla has been worked up clinically, radiographically, and pathologically. The case was surgically managed and followed up.

Pleomorphic adenoma of the palate.

Pleomorphic adenoma (PA) is the most common salivary gland tumor, accounting for about 40-70% of all major and minor salivary gland tumors. The commonest sites for intraoral PA are palate, buccal mucosa and lips. Palatal PA presents clinically as a painless, slow-growing mass found on posterior lateral aspect.

Giant aneurysmal bone cyst of the mandible.

The aneurysmal bone cyst is a type of pseudocysts of the jaw. It is a nonneoplastic lesion of the bone, characterized by replacement with fibro-osseous tissue containing blood-filled sinusoidal or cavernous spaces. The lesion remains a relatively uncommon finding in the facial bones, and the cause and pathogenesis are yet to be elucidated.

Calcifying epithelial odontogenic tumour: a case report.

Calcifying epithelial odontogenic tumour (CEOT) presenting at an unusual site is rare. The characteristic cytologic findings in association with radiologic features can help the cytopathologist and the surgeon in rendering a firm preoperative diagnosis of Calcifying Epithelial Odontogenic Tumour even at atypical sites such as maxilla. The purpose of this article is to report an additional case of CEOT and discuss the radiologic appearance, histologic features, clinical behavior and surgical management.

Cervical necrotizing fasciitis caused by dental infection: A review and case report.

Necrotizing fasciitis of the head and neck is an uncommon, potentially fatal , soft tissue infection characterized by extensive necrosis and gas formation in the subcutaneous tissue and fascia. The purpose of this report is to heighten the awareness of this infection. The article also outlines an appropriate management strategy for use in the treatment of these patients and reviews the literature along with a report of a case which was successfully managed.

Granular cell - Peripheral ameloblastoma: a rare variant.

Ameloblastoma is an epithelial odontogenic tumour of the jaw and exhibits diverse microscopic patterns which occurs either singly or in combination with other patterns. Peripheral ameloblastoma is a rare odontogenic soft tissue tumor, derived from epithelial and/or mesenchymal elements being part of the tooth-forming apparatus. The lesions responsible for approximately 1% to 5% of all cases of ameloblastoma affecting alveolar mucosa and gingiva occurring mainly, in the middle age.