Folic Acid-Conjugated Radioluminescent Calcium Tungstate Nanoparticles as Radio-Sensitizers for Cancer Radiotherapy.

Radiation therapy is a primary treatment modality for many forms of cancer. Normally, the highest tolerable dose of ionizing radiation is used to treat tumors, but limitations imposed by normal tissue complications present challenges for local tumor control. In light of this, a class of compounds called radio-sensitizers have been developed to enhance the effectiveness of radiation.

Selective Formation of Trimethylene Carbonate (TMC): Atmospheric Pressure Carbon Dioxide Utilization.

Carbon dioxide utilisation (CDU) is currently gaining increased interest due to the abundance of CO and its possible application as a C building block. We herein report the first example of atmospheric pressure carbon dioxide incorporation into oxetane to selectively form trimethylene carbonate (TMC), which is a significant challenge as TMC is thermodynamically less favoured than its corresponding co-polymer.

Observations on the modified Wenker synthesis of aziridines and the development of a biphasic system.

A cheap and reliable process for the modified Wenker cyclization to afford aziridines has been achieved using biphasic conditions for a range of amino alcohol starting materials. A 100 mmol "one-pot" process has also been devised, and the enantiopurity of the starting amino alcohol is retained in the aziridine product.

Electrosynthesis of cyclic carbonates from epoxides and atmospheric pressure carbon dioxide.

The use of CO(2) for the preparation of value-added compounds has dramatically increased due to increased global warming concerns. We herein report an electrochemical cell containing a copper cathode and a magnesium anode that effectively converts epoxides and carbon dioxide to cyclic carbonates under mild electrochemical conditions at atmospheric pressure.