Publications by authors named "Anish Adhikari"
Study Objective: There is an increasing trend in myocardial infarction (MI) hospitalizations in young individuals. The prevalence of modifiable cardiovascular risk factors is high in this population. This study aims to assess the prevalence of traditional and non-traditional cardiovascular risk factors among young patients with coronary artery disease (CAD) including novel lipid and dietary biomarkers with a focus on potential gender differences.
View Article and Find Full Text PDFCartilage acidic protein-1 (CRTAC1) is produced by several cell types, including Type 2 alveolar epithelial (T2AE) cells that are targeted by SARS-CoV2. Plasma CRTAC1 is known based on proteomic surveys to be low in patients with severe COVID-19. Using an ELISA, we found that patients treated for COVID-19 in an ICU almost uniformly had plasma concentrations of CRTAC1 below those of healthy controls.
View Article and Find Full Text PDFArticle Synopsis
- - Researchers studied the lasting effects of COVID-19 on DNA methylation in blood cells by analyzing samples from 15 people one year after their hospital discharge.
- - Out of 1,505 DNA regions affected by the illness, 71 regions showed persistent changes in methylation, indicating they remained differentially methylated after recovery.
- - Notably, 64 regions were found to be hypermethylated, while 7 were hypomethylated, marking the first evidence that DNA methylation changes can persist long after COVID-19 recovery.
Introduction: Chronic kidney disease (CKD) is greatly affected by social determinants of health. Whether low educational attainment is associated with incident CKD in young adults is unclear.
Methods: We evaluated the association of education with incident CKD in 3139 Coronary Artery Risk Development in Young Adults participants.
The US Food and Drug Administration issued a black box warning in 2012 regarding the association of statin use with cognitive impairment. This may deter patients and practitioners from using statins for guideline-directed indications. Large studies have not shown an increase in cognitive impairment with statin use.
View Article and Find Full Text PDFBackground: A total of 25,000 people in the UK have osteoporotic vertebral fracture (OVF). Evidence suggests that physiotherapy may have an important treatment role.
Objective: The objective was to investigate the clinical effectiveness and cost-effectiveness of two different physiotherapy programmes for people with OVF compared with a single physiotherapy session.