Oscillococcinum for upper respiratory tract infections and exacerbations in COPD: an observational, prospective study (OXITUNIS).

Background: Upper respiratory tract infections (URTIs) are a major cause of exacerbations in patients with chronic obstructive pulmonary disease (COPD). We assessed the effectiveness of Oscillococcinum in the protection from URTIs in patients with COPD who had been vaccinated against influenza infection over the 2018-2019 winter season.

Methods: Patients (=106; mean ± standard deviation age: 66.